Chlorpropham

Modify Date: 2025-08-23 02:35:47

Chlorpropham structure	Common Name	Chlorpropham
	CAS Number	101-21-3	Molecular Weight	213.661
	Density	1.2±0.1 g/cm3	Boiling Point	251.1±23.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₂ClNO₂	Melting Point	41°C
	MSDS	Chinese USA	Flash Point	105.7±22.6 °C
	Symbol	GHS07, GHS08, GHS09	Signal Word	Warning

Use of Chlorpropham

Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[1][2].

Name	chlorpropham
Synonym	More Synonyms

Description	Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Chlorpropham (1-20 μM; 6 d) inhibits cell division of D. salina cultures[2]. Chlorpropham (10 or 20 μM; 6 d) shows increasement of phytoene in D. salina cultures under red LED light[2].

Density	1.2±0.1 g/cm3
Boiling Point	251.1±23.0 °C at 760 mmHg
Melting Point	41°C
Molecular Formula	C₁₀H₁₂ClNO₂
Molecular Weight	213.661
Flash Point	105.7±22.6 °C
Exact Mass	213.055649
PSA	38.33000
LogP	3.49
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.561
Water Solubility	0.009 g/100 ml very poor

Chlorpropham MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FD8050000

CHEMICAL NAME :: Carbanilic acid, m-chloro-, isopropyl ester

CAS REGISTRY NUMBER :: 101-21-3

BEILSTEIN REFERENCE NO. :: 2211397

LAST UPDATED :: 199712

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: C10-H12-Cl-N-O2

MOLECULAR WEIGHT :: 213.68

WISWESSER LINE NOTATION :: GR CMVOY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1092 gm/kg/2Y-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 68250 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in spleen weight Blood - methemoglobinemia-carboxyhemoglobin

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3 gm/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 9 gm/kg

SEX/DURATION :: female 6-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Kidney

DOSE/DURATION :: 2500 ug/L

REFERENCE :: PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,638,1981 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,55,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,55,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3 JAN 1993

Symbol	GHS07, GHS08, GHS09
Signal Word	Warning
Hazard Statements	H302-H351-H373-H411
Precautionary Statements	P273-P301 + P312 + P330-P391-P501
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;N: Dangerous for the environment;F: Flammable;
Risk Phrases	R22
Safety Phrases	S61-S36/37-S26
RIDADR	UN 3077 9/PG 3
WGK Germany	2
RTECS	FD8050000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2924299035

1-Azido-3-chlor...

CAS#:3296-06-8

carbon monoxide

CAS#:201230-82-2

Isopropanol

CAS#:67-63-0

~94%

Chlorpropham

CAS#:101-21-3

Literature: Ren, Long; Jiao, Ning Chemical Communications, 2014 , vol. 50, # 28 p. 3706 - 3709

Potassium cyanate

CAS#:590-28-3

1-Bromo-3-chlor...

CAS#:108-37-2

Isopropanol

CAS#:67-63-0

~85%

Chlorpropham

CAS#:101-21-3

Literature: Yang, Xinye; Zhang, Yihua; Ma, Dawei Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2443 - 2446,4

3-Chloroaniline

CAS#:108-42-9

Chlorpropham

CAS#:101-21-3

Literature: Chemical Communications, , vol. 50, # 28 p. 3706 - 3709

Precursor 6
CAS#:3296-06-8 1-Azido-3-chlor... CAS#:201230-82-2 carbon monoxide CAS#:67-63-0 Isopropanol CAS#:590-28-3 Potassium cyanate
CAS#:108-37-2 1-Bromo-3-chlor... CAS#:108-42-9 3-Chloroaniline
DownStream 5
CAS#:1746-77-6 Isopropyl carbamate CAS#:27898-06-2 N-(5-Chloro-2-h... CAS#:34061-87-5 3-Chloro-5-hydr... CAS#:108-42-9 3-Chloroaniline
CAS#:2610-61-9 (3-HYDROXY-ADAM...

HS Code	2924299035
Summary	2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

[Survey of pesticide residues in imported frozen vegetables and fruits (1989.4~2008.3)].

Shokuhin Eiseigaku Zasshi 52(2) , 121-9, (2011)

A survey of pesticide residues in 595 imported frozen products on the Tokyo market from April 1989 to March 2008 was carried out. Forty three kinds of pesticides, including organophosphorus, organochl...

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009)

The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and keto...

The sprout inhibitors chlorpropham and 1,4-dimethylnaphthalene elicit different transcriptional profiles and do not suppress growth through a prolongation of the dormant state.

Plant Mol. Biol. 73(1-2) , 181-9, (2010)

Chlorpropham (CIPC) and 1,4-dimethylnapthalene (DMN) are used to control postharvest sprouting of potato tubers. CIPC alters microtubule structure and function resulting in inhibition of cell division...

Chlorpropham

chlor-IPC

1-methylethyl (3-chlorophenyl)carbamate

MFCD00037108

isopropyl 3-chlorocarbanilate

Carbamic acid, N-(3-chlorophenyl)-, 1-methylethyl ester

propan-2-yl (3-chlorophenyl)carbamate

propan-2-yl N-(3-chlorophenyl)carbamate

EINECS 202-925-7

Isopropyl m-chlorocarbanilate

Bud Nip

Taterpex

Isopropyl (3-chlorophenyl)carbamate

1-methylethyl N-(3-chlorophenyl)carbamate

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Chlorpropham
Price: Check
Purity: 98.0%
Delivery: 10 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Chlorpropham
Price: ￥128.0/5g ￥378.0/25g
Purity: 98.0%
Delivery: Inquiry
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Email: 2130147988@qq.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Chlorpropham
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Chlorpropham
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Chlorpropham
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 101-21-3 Chlorpropham
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Chlorpropham
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Chlorpropham

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Chlorpropham Biological Activity

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MSDS

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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