Chlorpropham

Modify Date: 2024-01-02 14:43:35

Chlorpropham Structure
Chlorpropham structure
Common Name Chlorpropham
CAS Number 101-21-3 Molecular Weight 213.661
Density 1.2±0.1 g/cm3 Boiling Point 251.1±23.0 °C at 760 mmHg
Molecular Formula C10H12ClNO2 Melting Point 41°C
MSDS Chinese USA Flash Point 105.7±22.6 °C
Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning

 Use of Chlorpropham


Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[1][2].

 Names

Name chlorpropham
Synonym More Synonyms

 Chlorpropham Biological Activity

Description Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[1][2].
Related Catalog
In Vitro Chlorpropham (1-20 μM; 6 d) inhibits cell division of D. salina cultures[2]. Chlorpropham (10 or 20 μM; 6 d) shows increasement of phytoene in D. salina cultures under red LED light[2].

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 251.1±23.0 °C at 760 mmHg
Melting Point 41°C
Molecular Formula C10H12ClNO2
Molecular Weight 213.661
Flash Point 105.7±22.6 °C
Exact Mass 213.055649
PSA 38.33000
LogP 3.49
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.561
Water Solubility 0.009 g/100 ml very poor

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD8050000
CHEMICAL NAME :
Carbanilic acid, m-chloro-, isopropyl ester
CAS REGISTRY NUMBER :
101-21-3
BEILSTEIN REFERENCE NO. :
2211397
LAST UPDATED :
199712
DATA ITEMS CITED :
28
MOLECULAR FORMULA :
C10-H12-Cl-N-O2
MOLECULAR WEIGHT :
213.68
WISWESSER LINE NOTATION :
GR CMVOY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1092 gm/kg/2Y-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
68250 mg/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in spleen weight Blood - methemoglobinemia-carboxyhemoglobin
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3 gm/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
9 gm/kg
SEX/DURATION :
female 6-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
2500 ug/L
REFERENCE :
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,638,1981 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,55,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,55,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3 JAN 1993

 Safety Information

Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning
Hazard Statements H302-H351-H373-H411
Precautionary Statements P273-P301 + P312 + P330-P391-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;N: Dangerous for the environment;F: Flammable;
Risk Phrases R22
Safety Phrases S61-S36/37-S26
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS FD8050000
Packaging Group I; II; III
Hazard Class 6.1
HS Code 2924299035

 Synthetic Route

~94%

Chlorpropham Structure

Chlorpropham

CAS#:101-21-3

Literature: Ren, Long; Jiao, Ning Chemical Communications, 2014 , vol. 50, # 28 p. 3706 - 3709

~85%

Chlorpropham Structure

Chlorpropham

CAS#:101-21-3

Literature: Yang, Xinye; Zhang, Yihua; Ma, Dawei Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2443 - 2446,4

~%

Chlorpropham Structure

Chlorpropham

CAS#:101-21-3

Literature: Chemical Communications, , vol. 50, # 28 p. 3706 - 3709

 Customs

HS Code 2924299035
Summary 2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

 Articles27

More Articles
[Survey of pesticide residues in imported frozen vegetables and fruits (1989.4~2008.3)].

Shokuhin Eiseigaku Zasshi 52(2) , 121-9, (2011)

A survey of pesticide residues in 595 imported frozen products on the Tokyo market from April 1989 to March 2008 was carried out. Forty three kinds of pesticides, including organophosphorus, organochl...

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009)

The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and keto...

The sprout inhibitors chlorpropham and 1,4-dimethylnaphthalene elicit different transcriptional profiles and do not suppress growth through a prolongation of the dormant state.

Plant Mol. Biol. 73(1-2) , 181-9, (2010)

Chlorpropham (CIPC) and 1,4-dimethylnapthalene (DMN) are used to control postharvest sprouting of potato tubers. CIPC alters microtubule structure and function resulting in inhibition of cell division...

 Synonyms

Chlorpropham
chlor-IPC
1-methylethyl (3-chlorophenyl)carbamate
MFCD00037108
isopropyl 3-chlorocarbanilate
Carbamic acid, N-(3-chlorophenyl)-, 1-methylethyl ester
propan-2-yl (3-chlorophenyl)carbamate
propan-2-yl N-(3-chlorophenyl)carbamate
EINECS 202-925-7
Isopropyl m-chlorocarbanilate
Bud Nip
Taterpex
Isopropyl (3-chlorophenyl)carbamate
1-methylethyl N-(3-chlorophenyl)carbamate
Top Suppliers:I want be here

  • DC Chemicals Limited
  • China
  • Product Name: Chlorpropham
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao




Get all suppliers and price by the below link:

Chlorpropham suppliers

Chlorpropham price

Related Compounds: More...