Name | (+)-corydaline |
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Synonyms |
4H-Dibenzo[de,g]quinolin-1-ol, 5,6,6a,7-tetrahydro-2,10,11-trimethoxy-6-methyl-, (6aS)-
4H-Dibenzo[de,g]quinolin-1-ol, 5,6,6a,7-tetrahydro-2,10,11-trimethoxy-6-methyl-, (S)- (S)-5,6,6a,7-Tetrahydro-2,10.11-trimethoxy-6-methyl-4H-dibenzo[de,q]quinolin-1-ol 2,10,11-Trimethoxy-6aa-aporphin-1-ol d-corydine glaucentrin glaucentrine O11-Methylcorytuberine (6aS)-2,10,11-Trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol |
Description | Corydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves. Corydine is efficient on inhibiting reverse transcriptase (RT) activity with an IC50 of 356.8 μg/mL. Corydine displays significant in vitro anti-HIV potential, inhibiting 40% of the HIV-1 reverse transcriptase enzyme activity at a concentration of 450 μg/mL of Corydine[1]. |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 505.7±50.0 °C at 760 mmHg |
Melting Point | 165-167ºC |
Molecular Formula | C20H23NO4 |
Molecular Weight | 341.401 |
Flash Point | 259.7±30.1 °C |
Exact Mass | 341.162720 |
PSA | 51.16000 |
LogP | 3.09 |
Vapour Pressure | 0.0±1.4 mmHg at 25°C |
Index of Refraction | 1.604 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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~% 476-69-7 |
Literature: Gadamer Archiv der Pharmazie (Weinheim, Germany), 1911 , vol. 249, p. 664 |
~% 476-69-7 |
Literature: Spaeth; Berger Chemische Berichte, 1931 , vol. 64, p. 2038,2043 |
~% 476-69-7 |
Literature: Gadamer Archiv der Pharmazie (Weinheim, Germany), 1911 , vol. 249, p. 664 |
~% 476-69-7 |
Literature: Gadamer Archiv der Pharmazie (Weinheim, Germany), 1911 , vol. 249, p. 664 |
~% 476-69-7 |
Literature: Karimova, S. U.; Israilov, I. A.; Yunusov, M. S.; Yunusov, S. Yu. Chemistry of Natural Compounds, 1980 , vol. 16, # 2 p. 177 - 180 Khimiya Prirodnykh Soedinenii, 1980 , # 2 p. 224 - 228 |
~% 476-69-7 |
Literature: Karimova, S. U.; Israilov, I. A.; Yunusov, M. S.; Yunusov, S. Yu. Chemistry of Natural Compounds, 1980 , vol. 16, # 2 p. 177 - 180 Khimiya Prirodnykh Soedinenii, 1980 , # 2 p. 224 - 228 |
~% 476-69-7 |
Literature: Gadamer Archiv der Pharmazie (Weinheim, Germany), 1911 , vol. 249, p. 664 |
~% 476-69-7 |
Literature: Gadamer Archiv der Pharmazie (Weinheim, Germany), 1911 , vol. 249, p. 664 |
Precursor 9 | |
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DownStream 0 |