52365-63-6

52365-63-6 structure

52365-63-6 structure

Name: dipivefrin
Chemical Name: dipivefrin
CAS Number: 52365-63-6
Molecular Formula: C₁₉H₂₉NO₅
Molecular Weight: 351.43700
Catalog: API Special medicine Ophthalmic medication
Create Date: 2018-08-23 18:50:31
Modify Date: 2024-01-02 08:51:58
Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-drug. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2].

Name	dipivefrin
Synonyms	Dipivefrina [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate AKPro Dipivefrine Dipivefrinum Dipivefrina [INN-Spanish] Dipivefrinum [INN-Latin] Dipivefrin [USAN] dipivalyl epinephrine Propine

Description	Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-drug. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	Human Endogenous Metabolite
References	[1]. Kass MA,et al. Dipivefrin and epinephrine treatment of elevated intraocular pressure: a comparative study. Arch Ophthalmol. 1979 Oct;97(10):1865-6. [2]. Alkholief M, et al. Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo. Saudi Pharm J. 2020 Aug;28(8):1019-1029.

Density	1.097 g/cm3
Boiling Point	473.7ºC at 760 mmHg
Melting Point	146-147°
Molecular Formula	C₁₉H₂₉NO₅
Molecular Weight	351.43700
Flash Point	240.3ºC
Exact Mass	351.20500
PSA	84.86000
LogP	3.23330
Index of Refraction	1.511

HS Code	2922509090

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%