Dipivefrin

Modify Date: 2024-01-02 08:51:58

Dipivefrin Structure
Dipivefrin structure
Common Name Dipivefrin
CAS Number 52365-63-6 Molecular Weight 351.43700
Density 1.097 g/cm3 Boiling Point 473.7ºC at 760 mmHg
Molecular Formula C19H29NO5 Melting Point 146-147°
MSDS N/A Flash Point 240.3ºC

 Use of Dipivefrin


Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-drug. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2].

 Names

Name dipivefrin
Synonym More Synonyms

 Dipivefrin Biological Activity

Description Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-drug. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Kass MA,et al. Dipivefrin and epinephrine treatment of elevated intraocular pressure: a comparative study. Arch Ophthalmol. 1979 Oct;97(10):1865-6.

[2]. Alkholief M, et al. Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo. Saudi Pharm J. 2020 Aug;28(8):1019-1029.

 Chemical & Physical Properties

Density 1.097 g/cm3
Boiling Point 473.7ºC at 760 mmHg
Melting Point 146-147°
Molecular Formula C19H29NO5
Molecular Weight 351.43700
Flash Point 240.3ºC
Exact Mass 351.20500
PSA 84.86000
LogP 3.23330
Index of Refraction 1.511

 Safety Information

HS Code 2922509090

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Dipivefrina
[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate
AKPro
Dipivefrine
Dipivefrinum
Dipivefrina [INN-Spanish]
Dipivefrinum [INN-Latin]
Dipivefrin [USAN]
dipivalyl epinephrine
Propine