DC Chemicals Limited
China
Product Name: Indoprofen
Price: $250.0/100mg $500.0/250mg $1000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

31842-01-0

31842-01-0 structure

31842-01-0 structure

Name: Indoprofen
Chemical Name: indoprofen
CAS Number: 31842-01-0
Molecular Formula: C₁₇H₁₅NO₃
Molecular Weight: 281.30600
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-07-08 13:34:38
Modify Date: 2024-01-05 18:09:53
Indoprofen is a non-steroidal anti-inflammatory drug, provide insight into treatments for spinal muscular atrophies.

Name	indoprofen
Synonyms	Praxis α-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID INDOPROFEN flosin Bor-ind Reumofe isindone flosint k4277 Reumofene

Description	Indoprofen is a non-steroidal anti-inflammatory drug, provide insight into treatments for spinal muscular atrophies.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology

Density	1.308g/cm3
Boiling Point	511.3ºC at 760mmHg
Melting Point	213-214°
Molecular Formula	C₁₇H₁₅NO₃
Molecular Weight	281.30600
Flash Point	263ºC
Exact Mass	281.10500
PSA	57.61000
LogP	3.10010
Index of Refraction	1.642
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MU6645000

CHEMICAL NAME :: Hydratropic acid, p-(1-oxo-2-isoindolinyl)-

CAS REGISTRY NUMBER :: 31842-01-0

LAST UPDATED :: 199309

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C17-H15-N-O3

MOLECULAR WEIGHT :: 281.33

WISWESSER LINE NOTATION :: T56 BVN DHJ CR DY1&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 84 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1100,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1100,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor Behavioral - ataxia

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 36,1037,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 84 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 112,291,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 38320 mg/kg/68W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes primarily in glomeruli Kidney, Ureter, Bladder - interstitial nephritis Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,742,1982

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H351
Precautionary Statements	P281-P301 + P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;
Risk Phrases	25-40
Safety Phrases	22-36/37/39-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
RTECS	MU6645000
HS Code	2918300090

Precursor 9
124-38-9 68327-79-7 36691-00-6 50712-64-6
59430-62-5 119-67-5 32868-25-0 19910-33-9
118-90-1
DownStream 2
53086-13-8 53086-14-9

HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%