167114-91-2
167114-91-2 structure
- Name: Autocamtide-2-Related Inhibitory Peptide trifluoroacetate salt
- Chemical Name: Autocamtide 2-related inhibitory peptide
- CAS Number: 167114-91-2
- Molecular Formula: C64H116N22O19
- Molecular Weight: 1822.12000
- Catalog: Signaling Pathways Autophagy Autophagy
- Create Date: 2018-12-23 12:44:30
- Modify Date: 2025-08-27 08:14:51
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Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
| Name | Autocamtide 2-related inhibitory peptide |
|---|---|
| Synonyms |
AIP [Ala9]-Autocamtide 2
Autocamtide-2-related inhibitory peptide |
| Description | Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. |
|---|---|
| Related Catalog | |
| Target |
IC50: 40 nM (CaMKII)[1]. |
| In Vitro | It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1]. |
| References |
| Molecular Formula | C64H116N22O19 |
|---|---|
| Molecular Weight | 1822.12000 |
| Exact Mass | 1821.07000 |
| PSA | 746.43000 |
| LogP | 8.46970 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 20/21/22-36 |
| Safety Phrases | 22-24/25-26 |
| RIDADR | NONH for all modes of transport |