142720-24-9
142720-24-9 structure
- Name: FGIN-1-27
- Chemical Name: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
- CAS Number: 142720-24-9
- Molecular Formula: C28H37FN2O
- Molecular Weight: 436.60500
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-12-19 07:11:53
- Modify Date: 2025-08-20 20:16:27
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FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions[1].
| Name | 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide |
|---|---|
| Synonyms |
MFCD00467704
Fgin 1 27 Lopac-D-8555 Tocris-0658 N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide |
| Description | FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions[1]. |
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| Related Catalog | |
| References |
| Density | 1.073g/cm3 |
|---|---|
| Boiling Point | 608.3ºC at 760mmHg |
| Molecular Formula | C28H37FN2O |
| Molecular Weight | 436.60500 |
| Flash Point | 321.7ºC |
| Exact Mass | 436.28900 |
| PSA | 36.10000 |
| LogP | 7.50570 |
| Vapour Pressure | 9.6E-15mmHg at 25°C |
| Index of Refraction | 1.562 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| Precursor 4 | |
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| DownStream 0 | |