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Related CAS#:

10129-56-3

10129-56-3 structure
10129-56-3 structure
  • Name: PETCM
  • Chemical Name: 1,1,1-trichloro-3-pyridin-4-ylpropan-2-ol
  • CAS Number: 10129-56-3
  • Molecular Formula: C8H8Cl3NO
  • Molecular Weight: 240.51400
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-12-28 13:26:09
  • Modify Date: 2024-01-05 17:34:57
  • PETCM is an activator of caspase-3. PETCM can induces cell apoptosis and stimulate apoptosome formation in HeLa cell cytosols[1].

Name 1,1,1-trichloro-3-pyridin-4-ylpropan-2-ol
Synonyms Apoptosis Activator I
PETCM
Description PETCM is an activator of caspase-3. PETCM can induces cell apoptosis and stimulate apoptosome formation in HeLa cell cytosols[1].
Related Catalog
Target

Caspase 3

References

[1]. [1].Jiang X, Kim HE, Shu H, et al. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science, 2003, 299(5604): 223-226.

Density 1.465g/cm3
Boiling Point 342.2ºC at 760mmHg
Molecular Formula C8H8Cl3NO
Molecular Weight 240.51400
Flash Point 160.8ºC
Exact Mass 238.96700
PSA 33.12000
LogP 2.35520
Vapour Pressure 2.94E-05mmHg at 25°C
Index of Refraction 1.579
Hazard Codes Xn: Harmful;
Risk Phrases 22
Safety Phrases 36
HS Code 2933399090

~66%

10129-56-3 structure

10129-56-3

Literature: Valeas S. p. A. Patent: US5039684 A1, 1991 ;

~66%

10129-56-3 structure

10129-56-3

Literature: VALEAS S.p.A., INDUSTRIA CHIMICA E FARMACEUTICA Patent: EP384450 A1, 1990 ;
Precursor  3

DownStream  0

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%