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593-84-0

593-84-0 structure
593-84-0 structure
  • Name: Guanidine thiocyanate
  • Chemical Name: Guanidine thiocyanate
  • CAS Number: 593-84-0
  • Molecular Formula: C2H6N4S
  • Molecular Weight: 118.16
  • Catalog: Chemical reagent Organic reagent Barium salt
  • Create Date: 2018-05-11 08:00:00
  • Modify Date: 2025-08-22 17:24:28
  • Guanidine thiocyanate is a chaotropic agent. Guanidine thiocyanate can be used as a protein denaturant and a nucleic acid protector in the extraction of DNA and RNA from cells[1].
Name Guanidine thiocyanate
Synonyms GUANIDINE RHODANIDE
Guanidine, thiocyanate (1:1)
Guandine thiocyanate
thiocyanic acid,guanidine salt
Guanidinethiocyanate
GUANIDINIUM RHODANIDE
MFCD00013027
Guanidine isothiocyanate
Guanidine thiocyanate
Guanidine thiocyanate (1:1)
Guanidine thiocyanat
Guanidinium thiocyanate
GdmSCN
guanidine monothiocyanate
usafek-705
GTC
Guanidiniumthiocyanat
EINECS 209-812-1
Description Guanidine thiocyanate is a chaotropic agent. Guanidine thiocyanate can be used as a protein denaturant and a nucleic acid protector in the extraction of DNA and RNA from cells[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Mason PE, et al. The hydration structure of guanidinium and thiocyanate ions: implications for protein stability in aqueous solution. Proc Natl Acad Sci U S A. 2003;100(8):4557-4561.
Density 1.103 g/mL at 20 °C
Boiling Point 132.9ºC at 760 mmHg
Melting Point 120-122 °C(lit.)
Molecular Formula C2H6N4S
Molecular Weight 118.16
Flash Point 34.2ºC
Exact Mass 118.031319
PSA 138.48000
LogP 0.73618
Index of Refraction n20/D 1.482
Storage condition Store at RT.
Stability Stability Stable, but light sensitive. Incompatible with acids (contact releases very toxic gas), strong oxidising agents.
Water Solubility H2O: 6 M at 20 °C, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XL1225000
CAS REGISTRY NUMBER :
593-84-0
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C-H5-N3.C-H-N-S
MOLECULAR WEIGHT :
118.18
WISWESSER LINE NOTATION :
ZYZUM &SHCN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302 + H312 + H332-H314-H412
Supplemental HS Contact with acids liberates very toxic gas.
Precautionary Statements P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R20/21/22;R32;R52/53
Safety Phrases S36/37-S61-S13
RIDADR 1759
WGK Germany 2
RTECS XL1225000
Packaging Group III
Hazard Class 8
HS Code 2925290090
HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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