70431-34-4

70431-34-4 structure

Name: Colominic acid sodium salt
Chemical Name: trisodium,N-[(2S,3R,4S)-2-[(1R)-1,2-dihydroxyethyl]-4-hydroxy-6-(2-hydroxyethoxy)oxan-3-yl]acetamide
CAS Number: 70431-34-4
Molecular Formula: C₃₃H₄₈N₃Na₃O₂₅
Molecular Weight: 955.70900
Catalog: Research Areas Infection
Create Date: 2018-12-31 11:47:33
Modify Date: 2024-01-08 08:48:00
Colominic acid sodium salt (Polysialic acid sodium salt) could be naturally isolated from the cell wall of Escherichia coli and animals, gives a red color which has an absorption maximum at 530 nm. Colominic acid sodium salt (Polysialic acid sodium salt) possesses anti-bacterial activity[1][2].

Name	trisodium,N-[(2S,3R,4S)-2-[(1R)-1,2-dihydroxyethyl]-4-hydroxy-6-(2-hydroxyethoxy)oxan-3-yl]acetamide
Synonyms	Colominic acid sodium salt from Escherichia coli MFCD00133197

Description	Colominic acid sodium salt (Polysialic acid sodium salt) could be naturally isolated from the cell wall of Escherichia coli and animals, gives a red color which has an absorption maximum at 530 nm. Colominic acid sodium salt (Polysialic acid sodium salt) possesses anti-bacterial activity[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology
In Vitro	Colominic acid (Polysialic acid) is an form of N-glycosylation with great specificity for its limited central nervous system targets, including the cell adhesion molecules neural cell adhesion molecule (NCAM) and synaptic cell adhesion molecule 1 (SynCAM1), and the receptor, neuropilin-2[2].
References	[1]. Guy T. Barry, et al. COLOMINIC ACID, A POLYMER OF N-ACETYLNEURAMINIC ACID. J Exp Med. 1958 Apr 1;107(4):507-21. [2]. Osama I Alwassil, et al. Design, synthesis, and structural elucidation of novel NmeNANAS inhibitors for the treatment of meningococcal infection. PLoS One. 2019 Oct 16;14(10):e0223413.

RIDADR	NONH for all modes of transport