28718-91-4

28718-91-4 structure

Name: DAPI dilactate
Chemical Name: 2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide,2-hydroxypropanoic acid
CAS Number: 28718-91-4
Molecular Formula: C₂₂H₂₇N₅O₆
Molecular Weight: 457.48
Create Date: 2016-05-23 20:06:58
Modify Date: 2024-07-18 11:44:04
DAPI (dilactate) is a blue fluorescent dye that preferentially binds dsDNA and binds to minor groove AT clusters. DAPI (dilactate) is combined with dsDNA, and the fluorescence was enhanced about 20-fold. DAPI (dilactate) can be used to identify the cell cycle and specifically stains the nucleus but not the cytoplasm. DAPI (dilactate) form is more soluble in water than DAPI (dihydrochloride) form. [1][2]

Name	2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide,2-hydroxypropanoic acid

Description	DAPI (dilactate) is a blue fluorescent dye that preferentially binds dsDNA and binds to minor groove AT clusters. DAPI (dilactate) is combined with dsDNA, and the fluorescence was enhanced about 20-fold. DAPI (dilactate) can be used to identify the cell cycle and specifically stains the nucleus but not the cytoplasm. DAPI (dilactate) form is more soluble in water than DAPI (dihydrochloride) form. [1][2]
References	[1]. Kapuscinski J. DAPI: a DNA-specific fluorescent probe. Biotech Histochem. 1995 Sep;70(5):220-33. [2]. Nazaroff CD, et al. Assessment of Lung Eosinophils In Situ Using Immunohistological Staining. Methods Mol Biol. 2021;2223:237-266.