DAPI dilactate

Modify Date: 2024-07-18 11:44:04

DAPI dilactate Structure
DAPI dilactate structure
Common Name DAPI dilactate
CAS Number 28718-91-4 Molecular Weight 457.48
Density N/A Boiling Point N/A
Molecular Formula C22H27N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DAPI dilactate


DAPI (dilactate) is a blue fluorescent dye that preferentially binds dsDNA and binds to minor groove AT clusters. DAPI (dilactate) is combined with dsDNA, and the fluorescence was enhanced about 20-fold. DAPI (dilactate) can be used to identify the cell cycle and specifically stains the nucleus but not the cytoplasm. DAPI (dilactate) form is more soluble in water than DAPI (dihydrochloride) form. [1][2]

 Names

Name 2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide,2-hydroxypropanoic acid

 DAPI dilactate Biological Activity

Description DAPI (dilactate) is a blue fluorescent dye that preferentially binds dsDNA and binds to minor groove AT clusters. DAPI (dilactate) is combined with dsDNA, and the fluorescence was enhanced about 20-fold. DAPI (dilactate) can be used to identify the cell cycle and specifically stains the nucleus but not the cytoplasm. DAPI (dilactate) form is more soluble in water than DAPI (dihydrochloride) form. [1][2]
References

[1]. Kapuscinski J. DAPI: a DNA-specific fluorescent probe. Biotech Histochem. 1995 Sep;70(5):220-33.  

[2]. Nazaroff CD, et al. Assessment of Lung Eosinophils In Situ Using Immunohistological Staining. Methods Mol Biol. 2021;2223:237-266.  

 Chemical & Physical Properties

Molecular Formula C22H27N5O6
Molecular Weight 457.48
Exact Mass 367.16400
PSA 173.06000
LogP 3.45490