306-03-6

EffectsMUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance may be toxic to central nervous system (CNS).
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a
highly toxic material may produce general deterioration of health by an accumulation in one or many human
organs.

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Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention.
Skin ContactIn case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated
clothing and shoes. Cover the irritated skin with an emollient. Wash clothing before reuse. Thoroughly clean
shoes before reuse. Get medical attention immediately.
Serious Skin ContactWash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention immediately.
Serious InhalationEvacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation
when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.
IngestionIf swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
attention immediately.
Serious IngestionNot available.

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Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsNot available.
Flammable LimitsNot available.
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various SubstancesNon-flammable in presence of shocks.
Explosion Hazards in Presence Slightly explosive in presence of open flames and sparks.
of Various SubstancesNon-explosive in presence of shocks.
Fire Fighting MediaSMALL FIRE: Use DRY chemical powder.
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks onAs with most organic solids, fire is possible at elevated temperatures
Fire Hazards
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust
Hazardsexplosion hazard.
Hyoscyamine Hydrobromide

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Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill
Poisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to
reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition

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Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Do not ingest. Do not breathe dust. Wear suitable
protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek
medical advice immediately and show the container or the label. Avoid contact with skin and eyes.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 8°C (46.4°F).
Refrigerate Sensitive to light. Store in light-resistant containers.

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Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection
Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure LimitsNot available.

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Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Powdered solid.)Slight.
Odor
TasteNot available.
Molecular Weight370.28 g/mole
ColorWhite.
pH (1% soln/water)Not available.
Boiling PointNot available.
Melting Point149°C (300.2°F)
Critical TemperatureNot available.
Bulk Density: 400 kg/m3
Specific Gravity
Vapor PressureNot applicable.
Not available.
Vapor Density
VolatilityNot available.
Not available.
Odor Threshold
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
Not available.
Dispersion Properties
SolubilityNot available.
Hyoscyamine Hydrobromide

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Section 10. Stability and Reactivity Data
The product is stable.
Stability
Instability TemperatureNot available.
Excess heat, dust generation, light
Conditions of Instability
Not available.
Incompatibility with various
substances
CorrosivityNot available.
Special Remarks onSensitive to light.
Reactivity
Special Remarks onNot available.
Corrosivity
PolymerizationWill not occur.

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Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsLD50: Not available.
LC50: Not available.
Chronic Effects on Humans May cause damage to the following organs: central nervous system (CNS).
Other Toxic Effects onHazardous in case of ingestion, of inhalation.
HumansSlightly hazardous in case of skin contact (irritant).
Special Remarks onNot available.
Toxicity to Animals
Special Remarks onNot available.
Chronic Effects on Humans
Special Remarks on otherAcute Potential Health Effects:
Toxic Effects on HumansSkin: May cause skin irritation.
Eyes: May cause eye irritation.
Inhalation: May cause respiratory tract irritation.
Ingestion: Harmful if swallowed. May cause gastrointestinal tract irritation with abdominal distension, suppressed
salivation, dry and burning mouth, difficult swallowing, marked thirst. May affect behavior/central nervous system,
respiratory system (dyspnea), cardiovascular system, vision. An anticholinergic agent. It can cause blurred
vision, photophobia, vasodilation, rapid and weak pulse, tachydardia, hyperpyrexia, excitement, muscular
incoordination, convulsions, agitation, restlessness, disturbed gait and speech, hallucinations, delirium, and pupil
dilation, bradycardia. It may also affect the liver. Effects suggested by analogy to (-)-hyoscyamine

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Section 12. Ecological Information
EcotoxicityNot available.
BOD5 and CODNot available.
Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the ProductsThe products of degradation are less toxic than the product itself.
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation
Hyoscyamine Hydrobromide

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Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

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Section 14. Transport Information
DOT ClassificationCLASS 6.1: Poisonous material.
: Alkaloid solid, n.o.s.(Hyoscyamine Hydrobromide) UNNA: 1544 PG: III
Identification
Not available.
Special Provisions for
Transport
DOT (Pictograms)

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Section 15. Other Regulatory Information and Pictograms
TSCA 8(b) inventory: Hyoscyamine Hydrobromide
Federal and State
Regulations
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has found
to cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found
to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
Other Classifications
DSCL (EEC)R25- Toxic if swallowed.S45- In case of accident or if you feel unwell,
seek medical advice immediately (show the
label where possible).
Health Hazard
HMIS (U.S.A.)2 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
2 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
Hyoscyamine Hydrobromide
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.

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SECTION 16 - ADDITIONAL INFORMATION
N/A