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6101-04-8

6101-04-8 structure
6101-04-8 structure
  • Name: STRYCHNINE HYDROCHLORIDE, DIHYDRATE
  • Chemical Name: 2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
  • CAS Number: 6101-04-8
  • Molecular Formula: C20H14ClN3O3
  • Molecular Weight: 379.79600
  • Create Date: 2017-04-17 15:44:34
  • Modify Date: 2024-01-09 18:43:41

Name 2-(2-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
Synonyms Strychnin,Hydrochlorid
strychnine,hydrochloride
2-(2-chlorophenoxy)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide
Density 1.398g/cm3
Boiling Point 626.4ºC at 760 mmHg
Molecular Formula C20H14ClN3O3
Molecular Weight 379.79600
Flash Point 332.6ºC
Exact Mass 379.07200
PSA 80.74000
LogP 5.21020
Index of Refraction 1.679

Section 1. Chemical Product and Company Identification
Strychnine HCl dihydrateCatalog
ST145
Common Name/
Number(s).
Trade Name
CAS#6101-04-8
Manufacturer
RTECSWL2430000
SPECTRUM QUALITY PRODUCTS INC.
TSCATSCA 8(b) inventory:
Strychnine HCl dihydrate
Commercial Name(s)Not available.
CI# Not available.
SynonymStrychnidin-10-one hydrochloride
IN CASE OF EMERGENCY
Strychnine Hydrochloride
Chemical Name
Chemical FamilyNot available.CALL (310) 516-8000
(C21H22N2O2)2.HCl.2H2O
Chemical Formula
SPECTRUM QUALITY PRODUCTS INC.

Section 2.Composition and Information on Ingredients
Exposure Limits
TWA (mg/m3)STEL (mg/m3) CEIL (mg/m3)
NameCAS #% by Weight
1) Strychnine HCl dihydrate6101-04-8100
Toxicological DataStrychnine HCl dihydrate:
on IngredientsORAL (LD50):Acute: 2 mg/kg [Rat].

Section 3. Hazards Identification
Potential Acute Health Effects Extremely hazardous in case of inhalation. Very hazardous in case of eye contact (irritant), of ingestion.
Hazardous in case of skin contact (irritant). Severe over-exposure can result in death. Inflammation of the eye is
characterized by redness, watering, and itching.
Potential Chronic HealthCARCINOGENIC EFFECTS: Not available.
EffectsMUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance is toxic to the nervous system.
The substance may be toxic to heart, central nervous system (CNS).
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a
highly toxic material may produce general deterioration of health by an accumulation in one or many human
organs.
Strychnine HCl dihydrate

Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention immediately.
Skin ContactIn case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes
before reuse. Get medical attention.
Serious Skin ContactWash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious InhalationEvacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek medical attention.
IngestionIf swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
attention immediately.
Serious IngestionNot available.

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsNot available.
Flammable LimitsNot available.
Products of CombustionThese products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
Fire Hazards in Presence of Not available.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks onNot available.
Fire Hazards
Special Remarks on Explosion Not available.
Hazards

Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill
Poisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to
reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition
Strychnine HCl dihydrate

Section 7. Handling and Storage
PrecautionsKeep locked up.. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk,
evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not
breathe dust. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical
advice immediately and show the container or the label. Avoid contact with skin and eyes.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area.

Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal ProtectionSplash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure LimitsNot available.

Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Powdered solid.)OdorOdorless.
Bitter.
Taste
Molecular Weight406.9 g/mole
White.
Color
Not available.
pH (1% soln/water)
Boiling PointNot available.
Melting PointDecomposes.
Critical TemperatureNot available.
Specific GravityNot available.
Not applicable.
Vapor Pressure
Vapor DensityNot available.
Not available.
Volatility
Odor ThresholdNot available.
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
Dispersion PropertiesSee solubility in water.
SolubilityPartially soluble in cold water.

Section 10. Stability and Reactivity Data
StabilityThe product is stable.
Instability TemperatureNot available.
Conditions of InstabilityNot available.
Incompatibility with variousNot available.
substances
CorrosivityNon-corrosive in presence of glass.
Strychnine HCl dihydrate
Special Remarks onNot available.
Reactivity
Special Remarks onNot available.
Corrosivity
PolymerizationWill not occur.

Section 11. Toxicological Information
Routes of EntryAbsorbed through skin. Eye contact. Inhalation. Ingestion.
Toxicity to AnimalsAcute oral toxicity (LD50): 2 mg/kg [Rat].
Chronic Effects on HumansCauses damage to the following organs: the nervous system.
May cause damage to the following organs: heart, central nervous system (CNS).
Other Toxic Effects onExtremely hazardous in case of inhalation.
HumansVery hazardous in case of ingestion.
Hazardous in case of skin contact (irritant).
Special Remarks onNot available.
Toxicity to Animals
Special Remarks onNot available.
Chronic Effects on Humans
Special Remarks on otherNot available.
Toxic Effects on Humans

Section 12. Ecological Information
EcotoxicityNot available.
Not available.
BOD5 and COD
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.
Toxicity of the ProductsThe products of degradation are less toxic.
of Biodegradation
Special Remarks on theNot available.
Products of Biodegradation

Section 13. Disposal Considerations
Waste Disposal

Section 14. Transport Information
DOT ClassificationCLASS 6.1: Poisonous material.
Identification: Strychnine salt (Strychnine hydrochloride) UNNA: 1692 PG: I
Marine Pollutant
Special Provisions for
Transport
Strychnine HCl dihydrate
DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
TSCA 8(b) inventory: Strychnine HCl dihydrate
Federal and State
SARA 302/304/311/312 extremely hazardous substances: Strychnine HCl dihydrate
Regulations
California
Proposition 65
Warnings
Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
Other ClassificationsWHMIS (Canada)
CLASS D-2B: Material causing other toxic effects (TOXIC).
DSCL (EEC)R28- Very toxic if swallowed.
R38- Irritating to skin.
R41- Risk of serious damage to eyes.
Health Hazard
HMIS (U.S.A.)3 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
3 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Strychnine HCl dihydrate
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Precursor  0

DownStream  3