6119-47-7
6119-47-7 structure
- Name: Quinine Hydrochloride Dihydrate
- Chemical Name: Quinine hydrochloride dihydrate
- CAS Number: 6119-47-7
- Molecular Formula: C20H29ClN2O4
- Molecular Weight: 396.908
- Catalog: API Antibiotics Other antibiotics
- Create Date: 2018-07-16 17:24:13
- Modify Date: 2026-07-04 18:45:43
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Quinine Hydrochloride Dihydrate is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste.Target: AntiparasiticQuinine is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine, which, unlike quinine, is an antiarrhythmic. Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine. In patients with cerebral malaria receiving the standard dose of 10 mg/kg every eight hours, plasma quinine concentrations consistently exceeded 10 mg/liter, reaching a peak 60 ± 25 hours (mean ± 1 S.D.) after treatment was begun and then declining. Quinine total clearances (CI) and total apparent volumes of distribution (Vd) were significantly lower than in uncomplicated malaria (CI, 0.92 ± 0.42 compared with 1.35 ± 0.6 ml/min/kg, p = 0.03; Vd, 1.18 ± 0.37 compared with 1.67 ± 0.34 liter/kg, p = 0.0013) [1].
| Name | Quinine hydrochloride dihydrate |
|---|---|
| Synonyms |
(R)(6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol hydrochloride
(-)-Quinine hydrochloride dihydrate Quinine monohydrochloride dihydrate Quinine hydrochL Quinine Hydrochloride DihydrateQ: What is Quinine Hydrochloride Dihydrate Q: What is the CAS Number of Quinine Hydrochloride Dihydrate Q: What is the storage condition of Quinine Hydrochloride Dihydrate Q: What e the applications of Quinine Hydrochloride Dihydrate (-)-QUININE HYDROCHLORIDE Quinine Hydfochloride (8α,9R)-6'-methoxy-cinchonan-9-ol,hydrochloride, hydrate (1:1:2) IpecacExtract (,) Quinine monohydrocloride dihydrate (R)(6-Methoxy-4-quinolyl)-(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanolHCLdihydrate Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-, hydrochloride, hydrate (1:1:2) (R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride dihydrate (R)(6-METHOXY-4-QUINOLYL)(5-VINYL-1-AZABICYCLO[2.2.2]OCT-2-YL)METHANOL HYDROCHLORIDE DIHYDRATE Quinine dihydrate hydrochloride Quinine HCl Dihydrate Quinine monohydrochloride dihydrate Vetec(TM) ade MFCD00151248 QUININE HCL NON-KOSHER (8α, 9R)-6′-Methoxycinchonan-9-ol monohydrochloride dihydrate QUININE HYDROCHLORIDE DIHYDRATE, FOR FLU ORESCENCE Quinine Hydrochloride Quinine.HCl.dihydrate, 1mg/ml in Ethanol (as free base) (R)(6-methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol monohydrochloride dihydrate Quinine Monohy QUININE MONOHYDROCHLORIDE DIHYDRATE (R)-(6-Methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanolhydrochloride Quinine hydrochloride,(R)-(6-Methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanolhydrochloride (R)-[(2S,4S,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol Cinchonan-9-ol, 6-methoxy-, monohydrochloride, dihydrate, (8.alpha.,9R) Quinine dihydrate monohydrochloride (-)-QUININE HYDROCHLORIDE PH EUR QUININE HYDROCHLORIDE DIHYDRATE EINECS 231-437-7 Quinine Monohydrochloride dihydrate, (total base), May contain up to Dihydroquinine QUININE MURIATE, DIHYDRATE QUININEHYDROCHLORIDE,DIHYDRATE,CRYSTAL Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, dihydrate, (8a,9R) (R)-(5-Ethenyl-1-azabicyclo[2.2.2]octan-7-yl)-(6-methoxyquinolin-4-yl)methanol dihydrate hydrochloride Quinine Hydrochloride Dihydrate> Quininehydrochloride,dihydrat QUININE HYDROCHLORIDE DIHYDRATE, PH EUR Quinidine Sulfate Impurity A as Hydrochloride Dihydrate (8α,9R)-6'-Methoxycinchonan-9-ol hydrochloride dihydrate (-)-Quinine hydrochloride 2-hydrate Quinine hydrochloride dihydrate //BP Quinine (hydrochloride dihydrate) CHININI HYDROCHLORIDUM Quinine Monohydrochloride DiHCl |
| Description | Quinine Hydrochloride Dihydrate is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste.Target: AntiparasiticQuinine is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine, which, unlike quinine, is an antiarrhythmic. Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine. In patients with cerebral malaria receiving the standard dose of 10 mg/kg every eight hours, plasma quinine concentrations consistently exceeded 10 mg/liter, reaching a peak 60 ± 25 hours (mean ± 1 S.D.) after treatment was begun and then declining. Quinine total clearances (CI) and total apparent volumes of distribution (Vd) were significantly lower than in uncomplicated malaria (CI, 0.92 ± 0.42 compared with 1.35 ± 0.6 ml/min/kg, p = 0.03; Vd, 1.18 ± 0.37 compared with 1.67 ± 0.34 liter/kg, p = 0.0013) [1]. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 633ºC at 760 mmHg |
|---|---|
| Melting Point | 115-116 °C (dec.)(lit.) |
| Molecular Formula | C20H29ClN2O4 |
| Molecular Weight | 396.908 |
| Flash Point | 122 °C |
| Exact Mass | 396.181580 |
| PSA | 64.05000 |
| LogP | 3.78450 |
| Index of Refraction | -250 ° (C=2, EtOH) |
| Storage condition | Store at -20°C |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H317-H334 |
| Precautionary Statements | P261-P280-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S22-S36/37-S45-S36/37/39-S26 |
| RIDADR | 1544 |
| WGK Germany | 3 |
| RTECS | VA7700000 |
| HS Code | 29392000 |
| Precursor 0 | |
|---|---|
| DownStream 5 | |
![trimethyl 2,2',2''-(3-hydroxy-6-(hydroxy(5-vinylquinuclidin-2-yl)methyl)-8-methoxy-1-oxo-2,3,5,6-tetrahydro-1H-3a,6-methanobenzo[d]pyrrolo[2,1-b][1,3]oxazepine-3,5,5-triyl)triacetate structure](https://image.chemsrc.com/caspic/298/121667-83-2.png)
![5-ethenyl-1-azabicyclo[2.2.2]octane-2-carbaldehyde structure](https://image.chemsrc.com/caspic/405/35189-41-4.png)
| HS Code | 29392000 |
|---|