Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PF-4778574
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: PF-4778574
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: PF-4778574
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

1219633-99-4

1219633-99-4 structure

1219633-99-4 structure

Name: PF-4778574
Chemical Name: N-{(3R,4S)-3-[4-(5-Cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-y l}-2-propanesulfonamide
CAS Number: 1219633-99-4
Molecular Formula: C₁₉H₂₂N₂O₃S₂
Molecular Weight: 390.52000
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2016-09-21 02:18:30
Modify Date: 2025-08-27 08:34:17
PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.

Name	N-{(3R,4S)-3-[4-(5-Cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-y l}-2-propanesulfonamide

Description	PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease
Target	EC50: 45 to 919 nM (AMPAR)[1]
References	[1]. Shaffer, C.L.; Scialis, R.J.; Lotarski, S.; et al. Defining themechanism-mediated exposure-response continuum of a novelAMPA receptor potentiator. 39th Annu Meet Soc Neurosci (October17-21, Chicago) 2009, Abst 883.17

Molecular Formula	C₁₉H₂₂N₂O₃S₂
Molecular Weight	390.52000
Exact Mass	390.10700
PSA	115.81000
LogP	4.95878

RIDADR	NONH for all modes of transport

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