104777-03-9

104777-03-9 structure

Name: 2-ethoxyethyl N-(4-(3-methyl-5-isoxazolyl)-2-thiazolyl)oxamate
Chemical Name: 2-ethoxyethyl 2-[[4-(3-methyl-1,2-oxazol-5-yl)-1,3-thiazol-2-yl]amino]-2-oxoacetate
CAS Number: 104777-03-9
Molecular Formula: C₁₃H₁₅N₃O₅S
Molecular Weight: 325.34000
Catalog: Research Areas Cardiovascular Disease
Create Date: 2016-01-25 22:43:39
Modify Date: 2023-01-17 07:27:26
Asobamast is a potent, orally active antiallergic agent that inhibits ige mediated passive pulmonary allergic responses in rats (ED50=4.7 mg/kg) and inhibits antigen-induced mediator release from sensitized guinea pig lung fragments[1].

Name	2-ethoxyethyl 2-[[4-(3-methyl-1,2-oxazol-5-yl)-1,3-thiazol-2-yl]amino]-2-oxoacetate
Synonyms	Asobamast Acetic acid,2-[[4-(3-methyl-5-isoxazolyl)-2-thiazolyl]amino]-2-oxo-,2-ethoxyethyl ester 2-ethoxyethyl{[4-(3-methyl-1,2-oxazol-5-yl)-1,3-thiazol-2-yl]amino}(oxo)acetate 2-ethoxyethyl N-[4-(3-methyl-5-isoxazolyl)-2-thiazolyl]oxamate Asobamastum [INN-Latin] UNII-F0R68O7C4V Asobamastum

Description	Asobamast is a potent, orally active antiallergic agent that inhibits ige mediated passive pulmonary allergic responses in rats (ED50=4.7 mg/kg) and inhibits antigen-induced mediator release from sensitized guinea pig lung fragments[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. D Chiarino, et al. N-(4-Isoxazolylthiazol-2-yl)oxamic acid derivatives as potent orally active antianaphylactic agents. J Med Chem. 1991 Feb;34(2):600-5.

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%