1173021-86-7
1173021-86-7 structure
- Name: 2-Ketoglutaric acid-d6
- Chemical Name: dideuterio 2,2,3,3-tetradeuterio-4-oxopentanedioate
- CAS Number: 1173021-86-7
- Molecular Formula: C5D6O5
- Molecular Weight: 152.13500
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
- Create Date: 2016-01-17 17:22:46
- Modify Date: 2024-01-09 12:53:54
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2-Ketoglutaric acid-d6 is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].
| Name | dideuterio 2,2,3,3-tetradeuterio-4-oxopentanedioate |
|---|---|
| Synonyms |
|A-Ketopentanoic acid-d6
2-Ketoglutaric acid-d6 2-Ketopentanedioic acid-d6 |A-Ketoglutaric acid-d6 |
| Description | 2-Ketoglutaric acid-d6 is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2]. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C5D6O5 |
|---|---|
| Molecular Weight | 152.13500 |
| Exact Mass | 152.05900 |
| PSA | 91.67000 |
| Symbol |
GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H315-H318-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |