1229002-07-6
1229002-07-6 structure
- Name: Tigecycline hydrate
- Chemical Name: (4S,4aS,5aR,12aR)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,hydrate
- CAS Number: 1229002-07-6
- Molecular Formula: C29H39N5O8.xH2O
- Molecular Weight: 603.66400
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2016-10-25 02:59:23
- Modify Date: 2025-08-25 23:02:22
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Tigecycline hydrate is a broad spectrum glycylcycline antibiotic. Tigecycline hydrate is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline hydrate is active against resistant strains of Gram-positive and Gram-negative bacteria.
| Name | (4S,4aS,5aR,12aR)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,hydrate |
|---|---|
| Synonyms |
Tigecyclin
9-t-Butylglycylamido-minocycline hydrate Tigecycline hydrate |
| Description | Tigecycline hydrate is a broad spectrum glycylcycline antibiotic. Tigecycline hydrate is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline hydrate is active against resistant strains of Gram-positive and Gram-negative bacteria. |
|---|---|
| Related Catalog |
| Molecular Formula | C29H39N5O8.xH2O |
|---|---|
| Molecular Weight | 603.66400 |
| Exact Mass | 603.29000 |
| PSA | 219.47000 |
| LogP | 2.48240 |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H319-H360 |
| Precautionary Statements | P201-P305 + P351 + P338-P308 + P313 |
| RIDADR | NONH for all modes of transport |
| RTECS | QI7619500 |