- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Quetiapine Fumarate
- Price: ￥155.0/1g ￥435.0/5g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Quetiapine Fumarate
- Price: $300.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Quetiapine fumarate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Quetiapine fumarate
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Quetiapine fumarate API
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
111974-72-2
111974-72-2 structure
- Name: Quetiapine Fumarate
- Chemical Name: quetiapine fumarate
- CAS Number: 111974-72-2
- Molecular Formula: C23H27N3O4S
- Molecular Weight: 441.54
- Catalog: API Nervous system medication Antipsychotic
- Create Date: 2018-07-03 22:20:20
- Modify Date: 2024-01-02 18:43:56
-
Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.IC50 value: Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
| Name | quetiapine fumarate |
|---|---|
| Synonyms |
MFCD03423782
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate Quetiapine Hemifumarate 2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol 2-butenedioate (2:1) Quetiapine fumarate Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, 2-butenedioate (2:1) (salt) Quetiapine hemifumarate salt Quetiapine (fumarate) |
| Description | Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.IC50 value: Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 556.5ºC at 760 mmHg |
|---|---|
| Melting Point | 174-176°C |
| Molecular Formula | C23H27N3O4S |
| Molecular Weight | 441.54 |
| Flash Point | 290.4ºC |
| PSA | 221.80000 |
| LogP | 4.04660 |
| Vapour Pressure | 3.22E-13mmHg at 25°C |
| Storage condition | -20°C Freezer |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H400 |
| Precautionary Statements | P273 |
| Hazard Codes | T,F |
| Risk Phrases | R45:May cause cancer. R10:Flammable. |
| Safety Phrases | S53-S45 |
| RIDADR | UN 3295 3/PG 3 |
| WGK Germany | 3 |
| RTECS | PC1075000 |
| Packaging Group | III |
| Hazard Class | 3 |
| HS Code | 2934999090 |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |