Quetiapine Fumarate
Modify Date: 2024-01-02 18:43:56
Quetiapine Fumarate structure
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Common Name | Quetiapine Fumarate | ||
|---|---|---|---|---|
| CAS Number | 111974-72-2 | Molecular Weight | 441.54 | |
| Density | N/A | Boiling Point | 556.5ºC at 760 mmHg | |
| Molecular Formula | C23H27N3O4S | Melting Point | 174-176°C | |
| MSDS | Chinese USA | Flash Point | 290.4ºC | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of Quetiapine FumarateQuetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.IC50 value: Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor. |
| Name | quetiapine fumarate |
|---|---|
| Synonym | More Synonyms |
| Description | Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.IC50 value: Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor. |
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| Related Catalog | |
| References |
| Boiling Point | 556.5ºC at 760 mmHg |
|---|---|
| Melting Point | 174-176°C |
| Molecular Formula | C23H27N3O4S |
| Molecular Weight | 441.54 |
| Flash Point | 290.4ºC |
| PSA | 221.80000 |
| LogP | 4.04660 |
| Vapour Pressure | 3.22E-13mmHg at 25°C |
| Storage condition | -20°C Freezer |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H400 |
| Precautionary Statements | P273 |
| Hazard Codes | T,F |
| Risk Phrases | R45:May cause cancer. R10:Flammable. |
| Safety Phrases | S53-S45 |
| RIDADR | UN 3295 3/PG 3 |
| WGK Germany | 3 |
| RTECS | PC1075000 |
| Packaging Group | III |
| Hazard Class | 3 |
| HS Code | 2934999090 |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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An understanding of modified release matrix tablets behavior during drug dissolution as the key for prediction of pharmaceutical product performance - case study of multimodal characterization of quetiapine fumarate tablets.
Int. J. Pharm. 484(1-2) , 235-45, (2015) Motivation for the study was the lack of dedicated and effective research and development (R&D) in vitro methods for oral, generic, modified release formulations. The purpose of the research was to as... |
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Quetiapine for the treatment of cocaine use disorder.
Drug Alcohol Depend. 149 , 18-24, (2015) Cocaine addiction continues to be a significant healthcare issue, yet there are no FDA approved medications for the treatment of cocaine use disorder within the United States.This 12-week, prospective... |
| MFCD03423782 |
| 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate |
| Quetiapine Hemifumarate |
| 2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol 2-butenedioate (2:1) |
| Quetiapine fumarate |
| Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, 2-butenedioate (2:1) (salt) |
| Quetiapine hemifumarate salt |
| Quetiapine (fumarate) |
- Shanghai Jizhi Biochemical Technology Co., Ltd
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- China
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- China
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- Purity: 99.0%
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Price: $66/10mM*1mLinDMSO
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