170569-87-6
170569-87-6 structure
- Name: Desmethyl Celecoxib
- Chemical Name: 4-[5-(phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
- CAS Number: 170569-87-6
- Molecular Formula: C16H12F3N3O2S
- Molecular Weight: 367.346
- Catalog: Signaling Pathways Immunology/Inflammation COX
- Create Date: 2016-11-12 14:16:54
- Modify Date: 2026-07-02 10:42:22
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Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%[1].
| Name | 4-[5-(phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide |
|---|---|
| Synonyms |
4-[5-phenyl-3-trifluoromethyl-1H-pyrazol-1-yl]benzene-sulfonamide
4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide 4-(5-phenyl-3-(trifluoromethyl) [3',6'-BIS(ACETYLOXY)-3-OXOSPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]-5-YL]-2-[[(5Z,8Z,11Z,14Z)-1-OXO-5,8,11,14-EICOSATETRAENYL]AMINO]ETHYL ESTER CBAMIC ACID Celecoxib-12 4-[5-phenyl-3-(trifluoromethyl) -1H-pyrazol-1-yl] benzenesulfonamide PTPBS Celecoxib Impurity L Desmethyl Celecoxib, 10 mM in DMSO Celecoxib Desmethyl Impurity Celecoxib Impurity 3 4-(5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1- yl)benzenesulfonamide 4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1yl]benzenesulfonamide 4-[5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide COX-2 INHIBITOR, PTPBS Benzenesulfonamide, 4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl] Celecoxib impurities1085 Celecoxib-004 CAY10454 1-(4-sulfonamidophenyl)-5-phenyl-3-(trifluoromethyl)-1H-pyrazole 4-[5-PHENYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE 4-[5-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOL-1-YL]BENZENESULFONAMIDE CAY10452 Celecoxib Impurity 3 1-HEXADECANOYL-2-(P-NITROPHENOXYSUCCINOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE |
| Description | Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%[1]. |
|---|---|
| Related Catalog | |
| Target |
COX-2:32 nM (IC50) |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 522.5±60.0 °C at 760 mmHg |
| Molecular Formula | C16H12F3N3O2S |
| Molecular Weight | 367.346 |
| Flash Point | 269.8±32.9 °C |
| Exact Mass | 367.060242 |
| PSA | 86.36000 |
| LogP | 3.75 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.613 |
| Hazard Codes | Xi |
|---|