548-90-3

548-90-3 structure

Name: Trichodesmine
Chemical Name: 2-chloro-4-(4-chlorophenyl)phenol
CAS Number: 548-90-3
Molecular Formula: C₁₂H₈Cl₂O
Molecular Weight: 239.09700
Catalog: Research Areas Metabolic Disease
Create Date: 2017-07-26 18:30:55
Modify Date: 2024-01-02 18:29:15
Trichodesmine is a dehydropyrrolizidine alkaloid. Trichodesmine can produces hepatotoxicty, pneumo- and neurotoxicity in vivo[1][2].

Name	2-chloro-4-(4-chlorophenyl)phenol
Synonyms	3,4'-Dichloro-4-biphenylol Trichodesmine [1,1'-Biphenyl]-4-ol,3,4'-dichloro

Description	Trichodesmine is a dehydropyrrolizidine alkaloid. Trichodesmine can produces hepatotoxicty, pneumo- and neurotoxicity in vivo[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
In Vitro	Trichodesmine produces pulmonary and hepatic lesions in donkeys[2].
References	[1]. Cooper RA, et, al. The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity. Proc West Pharmacol Soc. 1999;42:13-6. [2]. Pessoa CRM, et, al. Pulmonary and hepatic lesions caused by the dehydropyrrolizidine alkaloid-producing plants Crotalaria juncea and Crotalaria retusa in donkeys. Toxicon. 2013 Sep;71:113-20.