Trichodesmine

Modify Date: 2024-01-02 18:29:15

Trichodesmine Structure
Trichodesmine structure
Common Name Trichodesmine
CAS Number 548-90-3 Molecular Weight 239.09700
Density 1.29g/cm3 Boiling Point 546.5ºC at 760 mmHg
Molecular Formula C12H8Cl2O Melting Point 160-161 °C
MSDS N/A Flash Point 284.3ºC

 Use of Trichodesmine


Trichodesmine is a dehydropyrrolizidine alkaloid. Trichodesmine can produces hepatotoxicty, pneumo- and neurotoxicity in vivo[1][2].

 Names

Name 2-chloro-4-(4-chlorophenyl)phenol
Synonym More Synonyms

 Trichodesmine Biological Activity

Description Trichodesmine is a dehydropyrrolizidine alkaloid. Trichodesmine can produces hepatotoxicty, pneumo- and neurotoxicity in vivo[1][2].
Related Catalog
In Vitro Trichodesmine produces pulmonary and hepatic lesions in donkeys[2].
References

[1]. Cooper RA, et, al. The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity. Proc West Pharmacol Soc. 1999;42:13-6.

[2]. Pessoa CRM, et, al. Pulmonary and hepatic lesions caused by the dehydropyrrolizidine alkaloid-producing plants Crotalaria juncea and Crotalaria retusa in donkeys. Toxicon. 2013 Sep;71:113-20.

 Chemical & Physical Properties

Density 1.29g/cm3
Boiling Point 546.5ºC at 760 mmHg
Melting Point 160-161 °C
Molecular Formula C12H8Cl2O
Molecular Weight 239.09700
Flash Point 284.3ºC
Exact Mass 237.99500
PSA 20.23000
LogP 4.36600
Index of Refraction 1.571

 Safety Information

RIDADR UN 1544
Packaging Group III
Hazard Class 6.1(b)

 Synonyms

3,4'-Dichloro-4-biphenylol
Trichodesmine
[1,1'-Biphenyl]-4-ol,3,4'-dichloro