872254-32-5
872254-32-5 structure
- Name: NSCI
- Chemical Name: 1-[(4-methoxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione
- CAS Number: 872254-32-5
- Molecular Formula: C26H25N3O6S
- Molecular Weight: 507.55800
- Catalog: Signaling Pathways Apoptosis Caspase
- Create Date: 2017-08-25 06:43:23
- Modify Date: 2024-09-08 08:44:29
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Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1].
| Name | 1-[(4-methoxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione |
|---|---|
| Synonyms | Pyridine Analogue 21c |
| Description | Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
Caspase-3:14.5 ± 1.6 nM (IC50) Caspase-7:21.8 ± 3.5 nM (IC50) Caspase-6:>5000 nM (IC50) Caspase-1:>10000 nM (IC50) Caspase-8:>50000 nM (IC50) |
| References |
| Molecular Formula | C26H25N3O6S |
|---|---|
| Molecular Weight | 507.55800 |
| Exact Mass | 507.14600 |
| PSA | 114.49000 |
| LogP | 4.13550 |
| RIDADR | NONH for all modes of transport |
|---|