225110-25-8

225110-25-8 structure

Name: Falcarindiol
Chemical Name: (+)-(3R,8S)-falcarindiol
CAS Number: 225110-25-8
Molecular Formula: C₁₇H₂₄O₂
Molecular Weight: 260.37
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-05-02 08:00:00
Modify Date: 2024-01-04 10:46:20
(+)-(3R,8S)-Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC50 of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra[1][2]. Antineoplastic and anti-inflammatory activity[2].

Name	(+)-(3R,8S)-falcarindiol
Synonyms	(9Z)-1,9-Heptadecadiene-4,6-diyne-3,8-diol 1,9-Heptadecadiene-4,6-diyne-3,8-diol, (9Z)- Falcarindiol (9Z)-Heptadeca-1,9-diene-4,6-diyne-3,8-diol 1,9-HEPTADECADIENE-4,6-DIYNE-3,8-DIOL,(3R,8S,9Z)- (3R,8S)-Falcarindiol

Description	(+)-(3R,8S)-Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC50 of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra[1][2]. Antineoplastic and anti-inflammatory activity[2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 6 μM (Mycobacterium tuberculosis H37Ra)[1]
References	[1]. O'Neill T, et al. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins. J Ethnopharmacol. 2013 May 2;147(1):232-7. [2]. Kobaek-Larsen M, et al. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer. BMC Res Notes. 2018 Jun 27;11(1):411.

Hazard Codes	Xi

Precursor 0
DownStream 1
124-11-8

225110-25-8	55297-87-5
64813-10-1	557744-83-9