503610-43-3
503610-43-3 structure
- Name: Rosuvastatin Lactone
- Chemical Name: Rosuvastatin Lactone
- CAS Number: 503610-43-3
- Molecular Formula: C22H26FN3O5S
- Molecular Weight: 463.522
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-08-24 18:38:46
- Modify Date: 2025-08-21 10:51:28
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Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor)[1].
| Name | Rosuvastatin Lactone |
|---|---|
| Synonyms |
Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-
RosuvastatinLactone (3R,5R)-ROSUVASTATIN LACTONE Rosuvastatin lactone N-[4-(4-Fluorophenyl)-5-{(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]vinyl}-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide ROSUVASTATIN-5S-LACTONE |
| Description | Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor)[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 695.0±65.0 °C at 760 mmHg |
| Melting Point | 131℃ |
| Molecular Formula | C22H26FN3O5S |
| Molecular Weight | 463.522 |
| Flash Point | 374.1±34.3 °C |
| Exact Mass | 463.157715 |
| PSA | 118.07000 |
| LogP | 0.42 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.615 |
| Storage condition | -20℃ |
| Precursor 8 | |
|---|---|
| DownStream 0 | |
![E-(6-{2-[2-(N-methyl-N-methanesulfonylamino)-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-5-yl]vinyl}-[(4R,6S)-2,2-dimethyl-[1,3]dioxan-4-yl])-N-methoxy-N-methyl-acetamide structure](https://image.chemsrc.com/caspic/088/1353637-13-4.png)
![(6-{(E)-2-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]vinyl}-(4R,6S)-2,2-dimethyl[1,3]dioxan-4-yl)-acetic acid ethyl ester structure](https://image.chemsrc.com/caspic/132/851440-18-1.png)
![4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-methanol structure](https://image.chemsrc.com/caspic/286/147118-36-3.png)