838818-26-1
838818-26-1 structure
- Name: WIKI4
- Chemical Name: 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[3-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-
- CAS Number: 838818-26-1
- Molecular Formula: C29H23N5O3S
- Molecular Weight: 521.590
- Catalog: Biochemical Inhibitor Stem Cells & Wnt Signaling Paths (Stem Cells & Wnt) Wnt/beta-catenin inhibitor
- Create Date: 2016-02-02 11:35:43
- Modify Date: 2024-01-02 14:21:53
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WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM).
| Name | 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[3-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]- |
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| Synonyms |
2-(3-{[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}propyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[3-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]- wiki4 |
| Description | WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM). |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 783.1±70.0 °C at 760 mmHg |
| Molecular Formula | C29H23N5O3S |
| Molecular Weight | 521.590 |
| Flash Point | 427.4±35.7 °C |
| Exact Mass | 521.152161 |
| PSA | 117.20000 |
| LogP | 5.20 |
| Appearance | white to beige |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.716 |
| Storage condition | ?20°C |
| Water Solubility | DMSO: soluble10mg/mL, clear (warmed) |
| RIDADR | NONH for all modes of transport |
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