475473-26-8

475473-26-8 structure

Name: CORM-3
Chemical Name: Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)
CAS Number: 475473-26-8
Molecular Formula: C₅H₄ClNO₅Ru
Molecular Weight: 296.62800
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-12-06 19:21:40
Modify Date: 2024-01-03 18:39:00
CORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels[1][2][3].

Name	Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)
Synonyms	MFCD07364048

Description	CORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels[1][2][3].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Foresti R, et al. Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule. Br J Pharmacol. 2004 Jun;142(3):453-60. [2]. Lee DW, et al. Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages. Biochem Biophys Res Commun. 2017 Nov 18;493(2):957-963. [3]. Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-κB signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39.

Hazard Codes	N
RIDADR	NONH for all modes of transport