Top Suppliers:I want be here
Related CAS#:
1068-84-4 118317-76-3
119881-02-6 76387-79-6
57471-67-7 26767-88-4
53704-09-9 14097-00-8
171348-52-0 137401-45-7

1068-84-4

1068-84-4 structure
1068-84-4 structure
  • Name: Aminomalonic acid
  • Chemical Name: aminomalonic acid
  • CAS Number: 1068-84-4
  • Molecular Formula: C3H5NO4
  • Molecular Weight: 119.076
  • Catalog: Research Areas Cancer
  • Create Date: 2018-09-25 20:13:11
  • Modify Date: 2024-01-02 13:42:00
  • Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3].
Name aminomalonic acid
Synonyms Aminomalonic acid
2-aminopropanedioic acid
aminopropanedioic acid
Propanedioic acid, 2-amino-
Propanedioic acid, amino-
Description Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3].
Related Catalog
Target

Ki: 0.0023 M (L-asparagine synthetase from Leukemia 5178Y/AR), 0.0015 M (L-asparagine synthetase from mouse pancreas)[2]

References

[1]. Van Buskirk JJ, et al. Aminomalonic acid: identification in Escherichia coli and atherosclerotic plaque. Proc Natl Acad Sci U S A. 1984 Feb;81(3):722-5.

[2]. Milman HA, et al. Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase. Enzyme. 1979;24(1):36-47.

[3]. Kim HY, et al. Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling. Sci Rep. 2017 Aug 18;7(1):8864.
Density 1.7±0.1 g/cm3
Boiling Point 402.6±40.0 °C at 760 mmHg
Melting Point 240-245°C
Molecular Formula C3H5NO4
Molecular Weight 119.076
Flash Point 197.3±27.3 °C
Exact Mass 119.021858
PSA 100.62000
LogP -0.27
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.545
Hazard Codes Xi
HS Code 2922499990
HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Chemsrc provides CAS#:1068-84-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1068-84-4 | Chemsrc address: https://m.chemsrc.com/en/baike/1189855.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved