Aminomalonic acid

Modify Date: 2024-01-02 13:42:00

Aminomalonic acid structure	Common Name	Aminomalonic acid
	CAS Number	1068-84-4	Molecular Weight	119.076
	Density	1.7±0.1 g/cm3	Boiling Point	402.6±40.0 °C at 760 mmHg
	Molecular Formula	C₃H₅NO₄	Melting Point	240-245°C
	MSDS	N/A	Flash Point	197.3±27.3 °C

Use of Aminomalonic acid

Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3].

Name	aminomalonic acid
Synonym	More Synonyms

Description	Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3].
Related Catalog	Research Areas >> Cancer
Target	Ki: 0.0023 M (L-asparagine synthetase from Leukemia 5178Y/AR), 0.0015 M (L-asparagine synthetase from mouse pancreas)[2]
References	[1]. Van Buskirk JJ, et al. Aminomalonic acid: identification in Escherichia coli and atherosclerotic plaque. Proc Natl Acad Sci U S A. 1984 Feb;81(3):722-5. [2]. Milman HA, et al. Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase. Enzyme. 1979;24(1):36-47. [3]. Kim HY, et al. Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling. Sci Rep. 2017 Aug 18;7(1):8864.

Density	1.7±0.1 g/cm3
Boiling Point	402.6±40.0 °C at 760 mmHg
Melting Point	240-245°C
Molecular Formula	C₃H₅NO₄
Molecular Weight	119.076
Flash Point	197.3±27.3 °C
Exact Mass	119.021858
PSA	100.62000
LogP	-0.27
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.545

Hazard Codes	Xi
HS Code	2922499990

Precursor 10
CAS#:40885-82-3 2-(2-PHENYLHYDR... CAS#:6829-41-0 DIETHYL ISONITR... CAS#:62009-47-6 2-Aminomalonamide CAS#:600-33-9 chloromalonic acid
CAS#:600-31-7 2-Bromopropaned... CAS#:69645-51-8 2-nitropropaned... CAS#:118-78-5 2,4,6(1H,3H,5H)... CAS#:56-45-1 L-serine
CAS#:81601-40-3 L-threo-3-hydro... CAS#:302-72-7 DL-Alanine
DownStream 3
CAS#:473-90-5 Oxomalonic acid CAS#:56-40-6 Glycine CAS#:55327-87-2 Acetamidomaloni...

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%