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67-47-0

67-47-0 structure
67-47-0 structure
Name 5-hydroxymethylfurfural
Synonyms HMF
EINECS 200-654-9
5-(Hydroxymethyl)furan-2-carboxaldehyde
T5OJ BVH E1Q
5-(Hydroxymethyl)-2-furancarboxaldehyde
5-(Hydroxymethyl)furan-2-carbaldehyde
Aes-103
5-(Hydroxymethyl)furfural
5-Hydroxymethylfurfural
2-Furancarboxaldehyde, 5-(hydroxymethyl)-
MFCD00003234
2-furaldehyde, 5-(hydroxymethyl)-
Description 5-(Hydroxymethyl)furan-2-carbaldehyde, derived from lignocellulosic biomass, inhibits yeast growth and fermentation as stressors.
Related Catalog
Target

Yeast[1].

In Vitro It is found that furfural and HMF cause the attenuation of bulk translation activity and the assembly of cytoplasmic mRNP granules in Saccharomyces cerevisiae. Notably, a combination of furfural and HMF induce the remarkable repression of translation initiation and SG formation. Furfural and HMF can induce the formation of cytoplasmic mRNP granules, HMF also causes a gradual reduction in the polysome fraction and a concomitant increase in the 80S monosome fraction[1].
References

[1]. Iwaki A, et al. Biomass conversion inhibitors furfural and 5-hydroxymethylfurfural induce formation of messenger RNP granules and attenuate translation activity in Saccharomyces cerevisiae. Appl Environ Microbiol. 2013 Mar;79(5):1661-7.
Density 1.3±0.1 g/cm3
Boiling Point 291.5±30.0 °C at 760 mmHg
Melting Point 28-34 °C(lit.)
Molecular Formula C6H6O3
Molecular Weight 126.110
Flash Point 79.4±0.0 °C
Exact Mass 126.031693
PSA 50.44000
LogP -0.45
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.563
Storage condition 2-8°C
Stability Light Sensitive, Very Hygroscopic

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LT7031100
CHEMICAL NAME :
2-Furaldehyde, 5-(hydroxymethyl)-
CAS REGISTRY NUMBER :
67-47-0
BEILSTEIN REFERENCE NO. :
0110889
LAST UPDATED :
199712
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C6-H6-O3
MOLECULAR WEIGHT :
126.12
WISWESSER LINE NOTATION :
T5OJ BVH E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
2 gm/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 227,117,1989
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS LT7031100
Packaging Group III
HS Code 2932190090
HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
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title: CAS No. 67-47-0 | Chemsrc address: https://m.chemsrc.com/en/baike/1192568.html

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