120143-22-8

120143-22-8 structure

Name: 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose
Chemical Name: 1,2-di-o-acetyl-3-azido-3-deoxy-5-o-toluoyl-d-ribofuranose
CAS Number: 120143-22-8
Molecular Formula: C₁₇H₁₉N₃O₇
Molecular Weight: 377.35
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-17 14:57:07
Modify Date: 2024-01-23 15:58:10
1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1,2-di-o-acetyl-3-azido-3-deoxy-5-o-toluoyl-d-ribofuranose
Synonyms	3-azido-1,2-bis-O-acetyl-5-O-toluoyl-3-deoxy-D-ribofuranose 3-Azido-1H-[1,2,4]triazol 1H-1,2,4-Triazole,3-azido 3-Azido-1,2,4-triazol 3-azido-1H-[1,2,4]triazole 3-Azido-1,2,4-triazole 3-azido-1,2-di-O-acetyl-5-O-(p-toluoyl)-3-deoxy-D-ribofuranose

Description	1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312
Precautionary Statements	P280
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
RIDADR	NONH for all modes of transport