Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: MCLA hydrochloride
Price: ￥1738.0/10mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6-(4-METHOXYPHENYL)-2-METHYLIMIDAZO[1,2-A]PYRAZIN-3(7H)-ONE HYDROCHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

128322-44-1

128322-44-1 structure

128322-44-1 structure

Name: MCLA hydrochloride
Chemical Name: 2-Methyl-6-(4-Methoxyphenyl)-3,7-Dihydroimidazo[1,2-a]Pyrazin-3-One Hydrochloride
CAS Number: 128322-44-1
Molecular Formula: C₁₄H₁₄ClN₃O₂
Molecular Weight: 291.733
Catalog: Dye Reagents
Create Date: 2018-12-23 21:42:33
Modify Date: 2024-01-11 17:30:18
MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.

Name	2-Methyl-6-(4-Methoxyphenyl)-3,7-Dihydroimidazo[1,2-a]Pyrazin-3-One Hydrochloride
Synonyms	2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride 6-(4-methoxyphenyl)-2-methyl-7H-imidazo[1,2-a]pyrazin-3-one,hydrochloride MFCD00144728 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride (1:1) Imidazo[1,2-a]pyrazin-3(7H)-one, 6-(4-methoxyphenyl)-2-methyl-, hydrochloride (1:1) 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride MCLA hydrochloride

Description	MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
In Vitro	The non-specific luminescence remains almost constant for 10 min after the addition of MCLA hydrochloride (MCLA) and is not significantly influenced by SOD. The MCLA hydrochloride method is, however, 4.5-times more sensitive than the CLA method[1].
Kinase Assay	The standard reaction mixture contains 1×l0-7 M MCLA hydrochloride (MCLA), 5×10-5 M hypoxanthine, XOD (6.5 U), SOD (0.2 to 20 ng/mL) or none, and 50 mM Tris-HCl buffer containing 0.1 mM EDTA at pH 7.8, in a total volume of 3.0 mL. Chemiluminescence measurement is initiated by the addition of MCLA hydrochloride to the standard incubation mixture excluding XOD, continued for 4 min without additive and for an additional 4 min after the addition of XOD. Chemiluminescence is measured using a luminescence reader at 25°C[1].
References	[1]. Kimura H, et al. Highly sensitive and reliable chemiluminescence method for the assay of superoxide dismutase inhuman erythrocytes. FEBS Lett. 1988 Nov 7;239(2):347-50.

Boiling Point	410.3ºC at 760 mmHg
Molecular Formula	C₁₄H₁₄ClN₃O₂
Molecular Weight	291.733
Flash Point	201.9ºC
Exact Mass	291.077454
PSA	59.39000
LogP	2.80860
Vapour Pressure	3.95E-07mmHg at 25°C
Storage condition	2~8°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	F+
Safety Phrases	S22
RIDADR	NONH for all modes of transport
WGK Germany	3.0
HS Code	2933990090

119738-50-0 structure

119738-50-0

78-98-8 structure

78-98-8

~62%

128322-44-1 structure

128322-44-1

Literature: Bulletin of the Chemical Society of Japan, , vol. 65, # 9 p. 2475 - 2479

Precursor 2
119738-50-0 78-98-8
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%