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15263-52-2

15263-52-2 structure
15263-52-2 structure
  • Name: Cartap Hydrochloride
  • Chemical Name: cartap hydrochloride
  • CAS Number: 15263-52-2
  • Molecular Formula: C7H16ClN3O2S2
  • Molecular Weight: 273.804
  • Catalog: Chemical pesticide Insecticide Acaricide
  • Create Date: 2018-02-25 08:00:00
  • Modify Date: 2024-01-04 17:39:26
  • Cartap hydrochloride, an organonitrogen insecticide, can cause a marked irreversible Ca2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap hydrochloride significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells[1].
Name cartap hydrochloride
Synonyms S,S'-[2-(Dimethylamino)-1,3-propanediyl] dicarbamothioate hydrochloride (1:1)
vegetox
UNII-IWO0R06728
kartap
Cartapp
ntd2
Cartap hydrochloride
patap
Cadan
S,S'-[2-(Dimethylamino)propane-1,3-diyl] dicarbamothioate hydrochloride (1:1)
S,S'-[2-(Dimethylamino)-1,3-propanediyl] dicarbamothioate hydrochloride
Cartap monohydrochloride
EINECS 239-309-2
Padan
Carbamothioic acid, S,S'-[2-(dimethylamino)-1,3-propanediyl] ester, hydrochloride (1:1)
S,S’-[2-(dimethylamino)-1,3-propanediyl] dicarbamothioate hydrochloride (1:1)
Carta
S,S’-(2-dimethylaminotrimethylene) bis(thiocarbamate) hydrochloride
Cardan
padan4g
Description Cartap hydrochloride, an organonitrogen insecticide, can cause a marked irreversible Ca2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap hydrochloride significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells[1].
Related Catalog
References

[1]. Jiunn-Wang Liao, et al. Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology. 2006 Feb 15;219(1-3):73-84  

Density 1.42 g/cm3 (20ºC)
Boiling Point 407.2ºC at 760 mmHg
Melting Point 54-58 °C(lit.)
Molecular Formula C7H16ClN3O2S2
Molecular Weight 273.804
Flash Point 200.1ºC
Exact Mass 273.037231
PSA 140.02000
LogP 2.74300
Vapour Pressure 7.7E-07mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD1225000
CHEMICAL NAME :
Carbamic acid, thio-, S,S'-(2-(dimethylamino)trimethylene) ester, monohydrochloride
CAS REGISTRY NUMBER :
15263-52-2
LAST UPDATED :
199707
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C7-H15-N3-O2-S2.Cl-H
MOLECULAR WEIGHT :
273.83
WISWESSER LINE NOTATION :
ZVS1Y1SVZN1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 34,935,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
165 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 1,78,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,132,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 17,491,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
390 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HPBIA9 Herba Polonica. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.11- 1965- Volume(issue)/page/year: 21,53,1975 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
700 mg/kg
SEX/DURATION :
female 9-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 30,776,1971
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
300 mg/kg
SEX/DURATION :
female 8-13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 30,776,1971
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H312-H410
Precautionary Statements P273-P280-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;N:Dangerousfortheenvironment;
Risk Phrases R21/22;R50/53
Safety Phrases 2-36/37-60-61
RIDADR 2771
WGK Germany 3
RTECS FD1225000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2930200011
HS Code 2930200011
Summary 2930200011 s,s'-(2-(dimethylamino)propane-1,3-diyl) dicarbamothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

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