Cartap Hydrochloride

Modify Date: 2024-01-04 17:39:26

Cartap Hydrochloride Structure
Cartap Hydrochloride structure
Common Name Cartap Hydrochloride
CAS Number 15263-52-2 Molecular Weight 273.804
Density 1.42 g/cm3 (20ºC) Boiling Point 407.2ºC at 760 mmHg
Molecular Formula C7H16ClN3O2S2 Melting Point 54-58 °C(lit.)
MSDS Chinese USA Flash Point 200.1ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of Cartap Hydrochloride


Cartap hydrochloride, an organonitrogen insecticide, can cause a marked irreversible Ca2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap hydrochloride significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells[1].

 Names

Name cartap hydrochloride
Synonym More Synonyms

 Cartap Hydrochloride Biological Activity

Description Cartap hydrochloride, an organonitrogen insecticide, can cause a marked irreversible Ca2+-dependent contracture in both isolated mouse and rabbit phrenic nerve-diaphragms. Cartap hydrochloride significantly increases the level of endogenous reactive oxygen species (ROS) in C2C12 cells[1].
Related Catalog
References

[1]. Jiunn-Wang Liao, et al. Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology. 2006 Feb 15;219(1-3):73-84  

 Chemical & Physical Properties

Density 1.42 g/cm3 (20ºC)
Boiling Point 407.2ºC at 760 mmHg
Melting Point 54-58 °C(lit.)
Molecular Formula C7H16ClN3O2S2
Molecular Weight 273.804
Flash Point 200.1ºC
Exact Mass 273.037231
PSA 140.02000
LogP 2.74300
Vapour Pressure 7.7E-07mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD1225000
CHEMICAL NAME :
Carbamic acid, thio-, S,S'-(2-(dimethylamino)trimethylene) ester, monohydrochloride
CAS REGISTRY NUMBER :
15263-52-2
LAST UPDATED :
199707
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C7-H15-N3-O2-S2.Cl-H
MOLECULAR WEIGHT :
273.83
WISWESSER LINE NOTATION :
ZVS1Y1SVZN1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 34,935,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
165 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 1,78,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,132,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 17,491,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
390 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HPBIA9 Herba Polonica. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.11- 1965- Volume(issue)/page/year: 21,53,1975 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
700 mg/kg
SEX/DURATION :
female 9-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 30,776,1971
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
300 mg/kg
SEX/DURATION :
female 8-13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 30,776,1971

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H312-H410
Precautionary Statements P273-P280-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;N:Dangerousfortheenvironment;
Risk Phrases R21/22;R50/53
Safety Phrases 2-36/37-60-61
RIDADR 2771
WGK Germany 3
RTECS FD1225000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2930200011

 Customs

HS Code 2930200011
Summary 2930200011 s,s'-(2-(dimethylamino)propane-1,3-diyl) dicarbamothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

 Articles25

More Articles
Effects of various insecticides on the development of the egg parasitoid Trichogramma dendrolimi (Hymenoptera: Trichogrammatidae).

J. Econ. Entomol. 94(6) , 1340-3, (2001)

The toxicity of six insecticides, acephate, methomyl, ethofenprox, cartap, chlorfluazuron, and Bacillus thuringiensis (Bt) was tested on different developmental stages of the egg parasitoid, Trichogra...

Microbial biomass and carbon mineralization in agricultural soils as affected by pesticide addition.

Bull. Environ. Contam. Toxicol. 88(4) , 538-42, (2012)

A laboratory study was conducted with four pesticides, viz. a fungicide (carbendazim), two insecticides (chlorpyrifos and cartap hydrochloride) and an herbicide (pretilachlor) applied to a sandy clay ...

Assessment of the molluscicidal activities of Tribromosalan, Cartap and Chlorothalonil against Oncomelania hupensis.

Jpn. J. Med. Sci. Biol. 45(2) , 75-80, (1992)

Molluscicidal activities of Tribromosalan, Cartap and Chlorothalonil were evaluated in the laboratory and the field against Oncomelania hupensis, the intermediate host of Schistosoma japonicum in Chin...

 Synonyms

S,S'-[2-(Dimethylamino)-1,3-propanediyl] dicarbamothioate hydrochloride (1:1)
vegetox
UNII-IWO0R06728
kartap
Cartapp
ntd2
Cartap hydrochloride
patap
Cadan
S,S'-[2-(Dimethylamino)propane-1,3-diyl] dicarbamothioate hydrochloride (1:1)
S,S'-[2-(Dimethylamino)-1,3-propanediyl] dicarbamothioate hydrochloride
Cartap monohydrochloride
EINECS 239-309-2
Padan
Carbamothioic acid, S,S'-[2-(dimethylamino)-1,3-propanediyl] ester, hydrochloride (1:1)
S,S’-[2-(dimethylamino)-1,3-propanediyl] dicarbamothioate hydrochloride (1:1)
Carta
S,S’-(2-dimethylaminotrimethylene) bis(thiocarbamate) hydrochloride
Cardan
padan4g
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