1576-37-0

1576-37-0 structure

Name: BTS
Chemical Name: N-benzyl-4-methylbenzenesulfonamide
CAS Number: 1576-37-0
Molecular Formula: C₁₄H₁₅NO₂S
Molecular Weight: 261.33900
Catalog: Signaling Pathways Cytoskeleton Myosin
Create Date: 2018-07-05 20:04:33
Modify Date: 2024-01-02 10:58:08
BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uMTarget: Ca2+-stimulated myosin S1 ATPaseBTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.

Name	N-benzyl-4-methylbenzenesulfonamide
Synonyms	p-Toluenesulfonamide,N-benzyl N-Tosylbenzylamine N-Benzyl-4-methylbenzenesulfonamide N-Benzyl-p-toluenesulfonamide N-Benzyl-p-toluenesulphonamide N-Benzyl-4-methyl-benzenesulfonamide MFCD00159328 BTS

Description	BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uMTarget: Ca2+-stimulated myosin S1 ATPaseBTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.
Related Catalog	Signaling Pathways >> Cytoskeleton >> Myosin Research Areas >> Cancer
References	[1]. Cheung A, et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol. 2002 Jan;4(1):83-8.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,41,1953

RTECS	XT5490000
HS Code	2935009090

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%