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1576-37-0

1576-37-0 structure
1576-37-0 structure
  • Name: BTS
  • Chemical Name: N-benzyl-4-methylbenzenesulfonamide
  • CAS Number: 1576-37-0
  • Molecular Formula: C14H15NO2S
  • Molecular Weight: 261.33900
  • Catalog: Signaling Pathways Cytoskeleton Myosin
  • Create Date: 2018-07-05 20:04:33
  • Modify Date: 2026-07-02 18:28:03
  • BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uMTarget: Ca2+-stimulated myosin S1 ATPaseBTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.

Name N-benzyl-4-methylbenzenesulfonamide
Synonyms N-Methyl-N-(phenylmethyl)benzenesulfonamide
N-Tosylbenzenemethaneamine
4-methyl-n-(phenylmethyl)-benzenesulfonamid
N-BENZYL-P-TOLUENESULFONAMIDE
N-Benzyl-p-tosylaMide
CLN3
BTS (N-Benzyl-p-toluenesulfonamide
N-Benzyl-p-toluenesulfonamide
N-Tosylphenylmethanamine
N-Benzyl-p-toluenesulphonamide
BTS, Ca2+-stimulated myosin S1 ATPase
MFCD00159328
n-benzyl-p-toluenesulfonamid
N-BENZYL-4-METHYL-BENZENESULFONAMIDE
p-Toluenesulfonamide,N-benzyl
N-Benzyl-p-ToluenesulfonaMide (BTS)
N-Benzyl-4-methylbenzenesulfonamide
Battenin
LABOTEST-BB LT00786416
N-Benzyl-p-toluenesulfonamide >
BTS - - Calbiochem
N-Tosylbenzylamine
N-BENZYL-P-TOLUENESULPHONAMIDE
N-Benzyl-p-toluenesulfonic acid amine
Benzenesulfonamide,4-methyl-N-(phenylmethyl)
N-Benzyl-4-methyl-benzenesulfonamide
Benzyl(4-toluenesulfonyl)aMine
ANTI-CLN3 (CENTER) antibody produced in rabbit
4-METHYL-N-(PHENYLMETHYL)BENZENESULFONAMIDE
BTS, 10 mM in DMSO
Description BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uMTarget: Ca2+-stimulated myosin S1 ATPaseBTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.
Related Catalog
References

[1]. Cheung A, et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol. 2002 Jan;4(1):83-8.

Density 1.204 g/cm3
Boiling Point 419.1ºC at 760 mmHg
Melting Point 115 °C
Molecular Formula C14H15NO2S
Molecular Weight 261.33900
Flash Point 207.3ºC
Exact Mass 261.08200
PSA 54.55000
LogP 3.94520
Vapour Pressure 3.12E-07mmHg at 25°C
Index of Refraction 1.589
Storage condition Desiccate at RT

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT5490000
CHEMICAL NAME :
p-Toluenesulfonamide, N-benzyl-
CAS REGISTRY NUMBER :
1576-37-0
BEILSTEIN REFERENCE NO. :
2217277
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H15-N-O2-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,41,1953
RTECS XT5490000
HS Code 2935009090
HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
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