3343-39-3

3343-39-3 structure
3343-39-3 structure
  • Name: 2-Pyridylethylamine dihydrochloride
  • Chemical Name: 2-pyridin-2-ylethanamine,dihydrochloride
  • CAS Number: 3343-39-3
  • Molecular Formula: C7H12Cl2N2
  • Molecular Weight: 195.09
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-09-02 17:14:26
  • Modify Date: 2024-06-18 22:52:40
  • 2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1].

Name 2-pyridin-2-ylethanamine,dihydrochloride
Synonyms 2-PYRIDINEETHANAMINE DIHYDROCHLORIDE
2-Pyridylethylamine dihydrochloride
C7H10N2.2HCl
Description 2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1].
Related Catalog
References

[1]. Souza-Silva E, et al. Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model. Brain Res. 2020 May 15;1735:146757.  

Density 1.025g/cm3
Boiling Point 207.9ºC at 760mmHg
Molecular Formula C7H12Cl2N2
Molecular Weight 195.09
Flash Point 100.6ºC
Exact Mass 194.03800
PSA 38.91000
LogP 2.88710

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US1819170
CHEMICAL NAME :
Pyridine, 2-(2-aminoethyl)-, dihydrochloride
CAS REGISTRY NUMBER :
3343-39-3
LAST UPDATED :
198712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H10-N2.2Cl-H
MOLECULAR WEIGHT :
195.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
480 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle contraction or spasticity
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 30,178,1967
Precursor  1

DownStream  0