2-Pyridylethylamine dihydrochloride

Modify Date: 2025-08-27 09:15:41

2-Pyridylethylamine dihydrochloride structure	Common Name	2-Pyridylethylamine dihydrochloride
	CAS Number	3343-39-3	Molecular Weight	195.09
	Density	1.025g/cm3	Boiling Point	207.9ºC at 760mmHg
	Molecular Formula	C₇H₁₂Cl₂N₂	Melting Point	N/A
	MSDS	N/A	Flash Point	100.6ºC

Use of 2-Pyridylethylamine dihydrochloride

2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1].

Name	2-pyridin-2-ylethanamine,dihydrochloride
Synonym	More Synonyms

Description	2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Souza-Silva E, et al. Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model. Brain Res. 2020 May 15;1735:146757.

Density	1.025g/cm3
Boiling Point	207.9ºC at 760mmHg
Molecular Formula	C₇H₁₂Cl₂N₂
Molecular Weight	195.09
Flash Point	100.6ºC
Exact Mass	194.03800
PSA	38.91000
LogP	2.88710

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US1819170

CHEMICAL NAME :: Pyridine, 2-(2-aminoethyl)-, dihydrochloride

CAS REGISTRY NUMBER :: 3343-39-3

LAST UPDATED :: 198712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H10-N2.2Cl-H

MOLECULAR WEIGHT :: 195.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 480 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle contraction or spasticity

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 30,178,1967

2-amino-1-(2-py...

CAS#:75140-33-9

2-Pyridylethyla...

CAS#:3343-39-3

Literature: Burrus; Powell Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469

Precursor 1
CAS#:75140-33-9 2-amino-1-(2-py...
DownStream 0

2-PYRIDINEETHANAMINE DIHYDROCHLORIDE

2-Pyridylethylamine dihydrochloride

C7H10N2.2HCl

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