153436-22-7

153436-22-7 structure

Name: Gavestinel
Chemical Name: 3-[(E)-3-anilino-3-oxoprop-1-enyl]-4,6-dichloro-1H-indole-2-carboxylic acid
CAS Number: 153436-22-7
Molecular Formula: C₁₈H₁₂Cl₂N₂O₃
Molecular Weight: 375.21
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2019-01-01 12:24:13
Modify Date: 2025-08-22 17:37:21
Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].

Name	3-[(E)-3-anilino-3-oxoprop-1-enyl]-4,6-dichloro-1H-indole-2-carboxylic acid
Synonyms	Gavestinel

Description	Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. J F Hoke, et al. Pharmacokinetics of a glycine site antagonist (gavestinel) following multiple dosing in patients with acute stroke. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):867-72.