Gavestinel

Modify Date: 2025-08-22 17:37:21

Gavestinel Structure
Gavestinel structure
Common Name Gavestinel
CAS Number 153436-22-7 Molecular Weight 375.21
Density 1.561g/cm3 Boiling Point 701.1ºC at 760mmHg
Molecular Formula C18H12Cl2N2O3 Melting Point N/A
MSDS N/A Flash Point 377.8ºC

 Use of Gavestinel


Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].

 Names

Name 3-[(E)-3-anilino-3-oxoprop-1-enyl]-4,6-dichloro-1H-indole-2-carboxylic acid
Synonym More Synonyms

 Gavestinel Biological Activity

Description Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].
Related Catalog
References

[1]. J F Hoke, et al. Pharmacokinetics of a glycine site antagonist (gavestinel) following multiple dosing in patients with acute stroke. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):867-72.  

 Chemical & Physical Properties

Density 1.561g/cm3
Boiling Point 701.1ºC at 760mmHg
Molecular Formula C18H12Cl2N2O3
Molecular Weight 375.21
Flash Point 377.8ºC
Exact Mass 396.00400
PSA 85.02000
LogP 3.56310
Vapour Pressure 1.24E-20mmHg at 25°C
InChIKey WZBNEZWCNKUOSM-VOTSOKGWSA-N
SMILES O=C(C=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)Nc1ccccc1

 Synonyms

Gavestinel
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