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35404-50-3

35404-50-3 structure
35404-50-3 structure
  • Name: (2-Iminoimidazolidin-1-yl)acetic acid
  • Chemical Name: Cyclocreatine
  • CAS Number: 35404-50-3
  • Molecular Formula: C5H9N3O2
  • Molecular Weight: 143.144
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-03-31 08:00:00
  • Modify Date: 2024-01-02 11:10:25
  • Cyclocreatine is a Creatine analogue and acts as a potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine crosses membranes, enters the brain, and can be phosphorylated and dephosphorylated by creatine kinases[1].

Name Cyclocreatine
Synonyms 2-(2-amino-4,5-dihydroimidazol-1-yl)acetic acid
MFCD00134455
(2-Iminoimidazolidin-1-yl)acetic acid
(2-Amino-4,5-dihydro-1H-imidazol-1-yl)acetic acid
1H-Imidazole-1-acetic acid, 2-amino-4,5-dihydro-
Description Cyclocreatine is a Creatine analogue and acts as a potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine crosses membranes, enters the brain, and can be phosphorylated and dephosphorylated by creatine kinases[1].
Related Catalog
References

[1]. Salwa A Elgebaly, et al. Cyclocreatine protects against ischemic injury and enhances cardiac recovery during early reperfusion. Expert Rev Cardiovasc Ther. 2019 Sep;17(9):683-697.

[2]. Tyler K Ulland, et al. TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease. Cell. 2017 Aug 10;170(4):649-663.e13.

Density 1.6±0.1 g/cm3
Boiling Point 278.4±42.0 °C at 760 mmHg
Melting Point 25-28 °C(lit.)
Molecular Formula C5H9N3O2
Molecular Weight 143.144
Flash Point 122.2±27.9 °C
Exact Mass 143.069473
PSA 76.42000
LogP -1.99
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.660
Storage condition -20°C Freezer
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090
Precursor  1

DownStream  0

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%