(2-Iminoimidazolidin-1-yl)acetic acid

Modify Date: 2024-01-02 11:10:25

(2-Iminoimidazolidin-1-yl)acetic acid structure	Common Name	(2-Iminoimidazolidin-1-yl)acetic acid
	CAS Number	35404-50-3	Molecular Weight	143.144
	Density	1.6±0.1 g/cm3	Boiling Point	278.4±42.0 °C at 760 mmHg
	Molecular Formula	C₅H₉N₃O₂	Melting Point	25-28 °C(lit.)
	MSDS	Chinese USA	Flash Point	122.2±27.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of (2-Iminoimidazolidin-1-yl)acetic acid

Cyclocreatine is a Creatine analogue and acts as a potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine crosses membranes, enters the brain, and can be phosphorylated and dephosphorylated by creatine kinases[1].

Name	Cyclocreatine
Synonym	More Synonyms

Description	Cyclocreatine is a Creatine analogue and acts as a potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine crosses membranes, enters the brain, and can be phosphorylated and dephosphorylated by creatine kinases[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Salwa A Elgebaly, et al. Cyclocreatine protects against ischemic injury and enhances cardiac recovery during early reperfusion. Expert Rev Cardiovasc Ther. 2019 Sep;17(9):683-697. [2]. Tyler K Ulland, et al. TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease. Cell. 2017 Aug 10;170(4):649-663.e13.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

References

[1]. Salwa A Elgebaly, et al. Cyclocreatine protects against ischemic injury and enhances cardiac recovery during early reperfusion. Expert Rev Cardiovasc Ther. 2019 Sep;17(9):683-697.

[2]. Tyler K Ulland, et al. TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease. Cell. 2017 Aug 10;170(4):649-663.e13.

Density	1.6±0.1 g/cm3
Boiling Point	278.4±42.0 °C at 760 mmHg
Melting Point	25-28 °C(lit.)
Molecular Formula	C₅H₉N₃O₂
Molecular Weight	143.144
Flash Point	122.2±27.9 °C
Exact Mass	143.069473
PSA	76.42000
LogP	-1.99
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.660
Storage condition	-20°C Freezer

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2933990090

Precursor 1
CAS#:63784-10-1 2-(3-benzyl-2-i...
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synergistic action of dendritic mitochondria and creatine kinase maintains ATP homeostasis and actin dynamics in growing neuronal dendrites.

J. Neurosci. 35(14) , 5707-23, (2015)

The distribution of mitochondria within mature, differentiated neurons is clearly adapted to their regional physiological needs and can be perturbed under various pathological conditions, but the func...

Pharmacological identification of a guanidine-containing β-alanine analogue with low micromolar potency and selectivity for the betaine/GABA transporter 1 (BGT1).

Neurochem. Res. 39(10) , 1988-96, (2014)

The γ-aminobutyric acid (GABA) transporters (GATs) are key membrane transporter proteins involved in the termination of GABAergic signaling at synapses in the mammalian brain and proposed drug targets...

Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase.

Int. J. Cancer 78(1) , 46-52, (1998)

Cyclocreatine (1-carboxymethyl-2-iminoimidazolidine), an analog of creatine and a substrate for creatine kinase (EC 2.7.3.2), inhibits the stimulated motility of tumor cells which possess creatine kin...

2-(2-amino-4,5-dihydroimidazol-1-yl)acetic acid

MFCD00134455

(2-Iminoimidazolidin-1-yl)acetic acid

(2-Amino-4,5-dihydro-1H-imidazol-1-yl)acetic acid

1H-Imidazole-1-acetic acid, 2-amino-4,5-dihydro-