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9015-68-3

9015-68-3 structure
9015-68-3 structure
  • Name: asparaginase
  • Chemical Name: L-Asparaginase
  • CAS Number: 9015-68-3
  • Molecular Formula: C7H5NOS
  • Molecular Weight: 151.186
  • Catalog: Biochemical Enzymes and coenzymes
  • Create Date: 2018-03-15 08:00:00
  • Modify Date: 2024-01-08 10:19:47
  • L-Asparaginase (L-​ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1].

Name L-Asparaginase
Synonyms IUB: 3.5.4.4
Benzisothiazolone
L-ASPARAGINASE
T56 BSMVJ
ASPARAGINASE
benzo[d]isothiazol-3-one
1,2-Benzisothiazol-3(2H)-one
EC 3.5.1.1
T56 BSNJ DQ
crasnitin
L-ASPARAGINE AMIDOHYDROLASE
1,2-Benzothiazol-3(2H)-one
elspar
1,2-Benzisothiazol-3-ol
1,2-Benzothiazol-3-ol
Benzisothiazolone (BIT)
colaspase
Description L-Asparaginase (L-​ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1].
Related Catalog
References

[1]. Piatkowska-Jakubas B, et al. Use of L-asparaginase in acute lymphoblastic leukemia: recommendations of the Polish Adult Leukemia Group. Pol Arch Med Wewn. 2008 Nov;118(11):664-9.

Density 1.4±0.1 g/cm3
Boiling Point 204.5±23.0 °C at 760 mmHg
Molecular Formula C7H5NOS
Molecular Weight 151.186
Flash Point 77.5±22.6 °C
Exact Mass 151.009186
LogP 1.78
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.745
Storage condition 2-8°C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H317-H361
Precautionary Statements P280
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T,Xn
Risk Phrases 61-42/43-63
Safety Phrases 53-22-36/37/39-45-36/37
RIDADR 3249
WGK Germany 3
RTECS CI9000000
Packaging Group II