9028-56-2

9028-56-2 structure

Name: 3alpha-hydroxysteroid dehydrogenase
Chemical Name: Dehydrogenase 3alpha-hydroxy steroid
CAS Number: 9028-56-2
Molecular Formula:
Molecular Weight:
Catalog: API Antibiotics Other antibiotics
Create Date: 2018-11-26 08:22:56
Modify Date: 2024-01-06 19:45:48
3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism[1].

Name	Dehydrogenase 3alpha-hydroxy steroid
Synonyms	ALPHA-HYDROXYSTEROID DEHYDROGENASE 3ALPHA-HYDROXYSTEROID: NAD[P]+ OXIDOREDUCTASE EC 1.1.1.50 EC: 1.1.1.50 3alpha-hydroxysteroid dehydrogenase F. pseu. test. ~9 U/mg 3alpha-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni Dehydrogenase, 3alpha-hydroxy steroid

Description	3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism[1].
Related Catalog	Research Areas >> Endocrinology
References	[1]. Anne Z Steiner, et al. 3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism. J Clin Endocrinol Metab. 2008 Apr;93(4):1298-303.

Appearance	ammonium sulfate suspension
Storage condition	2-8°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
WGK Germany	3