Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Native Calf Adenosine Deaminase
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Native Calf Adenosine Deaminase
Price: ￥Inquiry/1mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

9026-93-1

9026-93-1 structure

9026-93-1 structure

Name: Native Calf Adenosine Deaminase
Chemical Name: Adenosine deaminase
CAS Number: 9026-93-1
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Metabolic Enzyme/Protease Adenosine Deaminase
Create Date: 2018-12-17 19:38:39
Modify Date: 2024-01-02 10:22:50
Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively.

Name	Adenosine deaminase
Synonyms	adenosine deaminase type viii adenosine deaminase type ix MFCD00081287 human adenosine deaminase adenosine deaminase adenosine deaminase, bovine intestine ec 3.5.4.4 adenosine deaminase type v Native Calf Adenosine Deaminase

Description	Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Adenosine Deaminase Research Areas >> Inflammation/Immunology
In Vitro	Adenosine deaminase (ADA; EC 3.5.4.4) catalyzes the irreversible deamination of adenosine and 2′-deoxyadenosine to inosine and 2′-deoxyinosine, respectively. Adenosine deaminase is implicated in purine metabolism and distributed in most mammalian tissues. Genetic Adenosine deaminase deficiency results in lymphopenia and severe combined immunodeficiency disease by decreasing the differentiation and maturation of lymphoid cells[1]. Adenosine deaminase is a signaling molecule related to the activation of T lympho-cytes, making it a useful inflammation marker, especially for menin-gitis and tuberculous pleuritis[2].
References	[1]. Tian X, et al. Probing inhibition mechanisms of adenosine deaminase by using molecular dynamics simulations. PLoS One. 2018 Nov 16;13(11):e0207234. [2]. Silva Dalsasso Joaquim L, et al. Analytical validation of an in-house method for adenosine deaminase determination. J Clin Lab Anal. 2018 Nov 29:e22823.

Storage condition	2-8C

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
RIDADR	NONH for all modes of transport