1276732-89-8

1276732-89-8 structure
1276732-89-8 structure
  • Name: Carbidopa-d3
  • Chemical Name: (s)-(-)-Carbidopa-d3
  • CAS Number: 1276732-89-8
  • Molecular Formula: C10H11D3N2O4
  • Molecular Weight: 229.25
  • Create Date: 2018-12-01 14:22:59
  • Modify Date: 2024-01-04 11:56:31

Name (s)-(-)-Carbidopa-d3
Synonyms Benzene-2,3,6-d3-propanoic acid, α-hydrazinyl-4,5-dihydroxy-α-methyl-, (αS)-
(2S)-3-[3,4-Dihydroxy(2H3)phenyl]-2-hydrazino-2-methylpropanoic acid
Description Carbidopa-d3 是 Carbidopa氘代物[1]。
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Density 1.4±0.1 g/cm3
Boiling Point 528.7±50.0 °C at 760 mmHg
Molecular Formula C10H11D3N2O4
Molecular Weight 229.25
Flash Point 273.5±30.1 °C
Exact Mass 229.114182
LogP -0.19
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.641