- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Epidermal Growth Factor
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Epidermal Growth Factor
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
62253-63-8
62253-63-8 structure
- Name: Epidermal Growth Factor
- Chemical Name: Epidermal Growth Factor
- CAS Number: 62253-63-8
- Molecular Formula: C270H401N73O83S7
- Molecular Weight: 6221.96723999994
- Catalog: API Hormone and endocrine-regulating drugs other
- Create Date: 2018-03-02 08:00:00
- Modify Date: 2024-01-02 10:08:42
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Epidermal growth factor (EGF) is the key regulatory factor in promoting cell survival. Epidermal growth factor (EGF) signaling pathways are related with apoptosis. Loss of Epidermal growth factor (EGF) leads to embryonic or perinatal lethality with abnormalities in multiple organs. Epidermal growth factor (EGF) can stimulate reactive oxygen species (ROS) production for a short period of time in cells. Epidermal growth factor (EGF) can be used to research development and cancer[1][2].
| Name | Epidermal Growth Factor |
|---|---|
| Synonyms |
nepidermin
MFCD00132565 EINECS 263-468-7 rh-EGF |
| Description | Epidermal growth factor (EGF) is the key regulatory factor in promoting cell survival. Epidermal growth factor (EGF) signaling pathways are related with apoptosis. Loss of Epidermal growth factor (EGF) leads to embryonic or perinatal lethality with abnormalities in multiple organs. Epidermal growth factor (EGF) can stimulate reactive oxygen species (ROS) production for a short period of time in cells. Epidermal growth factor (EGF) can be used to research development and cancer[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Apoptosis, ROS[1][2] |
| In Vitro | Epidermal growth factor (EGF) (500 ng/mL; 0-20 min) can induce the production of ROS in A431 cells[1]. Epidermal growth factor (EGF)-induced tyrosine phosphorylation of various cellular proteins was completely blocked in A431 cells containing exogenous catalase[1]. |
| In Vivo | Epidermal growth factor (EGF) (Osmotic pump delivered over 8 days at 10 pg/day) exhibits a highly significant stimulatory effect on wound closure in male mice[3]. Animal Model: C57BL6J and CBA mice (0.5-cm2 full-thickness back wound was cut out of the center of the back)[3] Dosage: 10 μg/day Administration: Osmotic pump delivered over 8 days at 10 pg/day Result: Exhibited a highly significant (P < 0.001) stimulatory effect on wound closure over 6 days in male mice. |
| Molecular Formula | C270H401N73O83S7 |
|---|---|
| Molecular Weight | 6221.96723999994 |
| Appearance | powder |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | KB4518000 |