126422-57-9

126422-57-9 structure

Name: Bis-propargyl-PEG2
Chemical Name: α,ω-bis(O-propargyl)diethylene glycol
CAS Number: 126422-57-9
Molecular Formula: C₁₀H₁₄O₃
Molecular Weight: 182.21600
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-14 02:55:57
Modify Date: 2024-01-21 12:22:02
Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2].

Name	α,ω-bis(O-propargyl)diethylene glycol
Synonyms	3-[2-(2-prop-2-ynyloxyethoxy)ethoxy]propyne bis-O-propargyl-di(ethylene glycol) 4,7,10-trioxahexadeca-1,12-diyne 4,7,10-trioxatrideca-1,12-diyne bis(2-propynoxyethyl)ether 4,7,10-trioxatrideca-1,12-diine

Description	Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	Bis-propargyl-PEG2 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].
References	[1]. Shenoi RA, et al. Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators. Biomacromolecules. 2012 Oct 8;13(10):3018-30. [2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.