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1355324-14-9 1628805-46-8
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1355324-14-9

1355324-14-9 structure
1355324-14-9 structure
  • Name: IDH-C227
  • Chemical Name: 2-((4-cyanophenyl)amino)-N-(2-(cyclohexylamino)-2-oxo-1-(o-tolyl)ethyl)-N-(3-fluorophenyl)acetamide
  • CAS Number: 1355324-14-9
  • Molecular Formula: C30H31FN4O2
  • Molecular Weight: 498.59100
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Isocitrate Dehydrogenase (IDH)
  • Create Date: 2018-03-25 16:58:54
  • Modify Date: 2024-01-11 19:37:40
  • IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].
Name 2-((4-cyanophenyl)amino)-N-(2-(cyclohexylamino)-2-oxo-1-(o-tolyl)ethyl)-N-(3-fluorophenyl)acetamide
Description IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].
Related Catalog
In Vitro IDH-C227 shows anticancer effcts, with IC50 values of <0.1 μM and 0.25 μM against HT1080 and U87MG cells, respectively[1].
References

[1]. Hanumantha Rao Madala, et al. Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies. Cancers (Basel). 2018 Feb 11;10(2):49.
Molecular Formula C30H31FN4O2
Molecular Weight 498.59100
Exact Mass 498.24300
PSA 85.23000
LogP 6.10498

Chemsrc provides CAS#:1355324-14-9 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1355324-14-9 | Chemsrc address: https://m.chemsrc.com/en/baike/1211158.html

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